disease was defined as presence of ischemic heart disease, stroke, transient ischemic attack or peripheral artery disease (4,12).
SAN DIEGO - Depression is a significant independent predictor of increased mortality and may increase the risk of macrovascular
events in adults with type 2 diabetes, a data analysis showed.
MYTH - Future complications are inevitable "Type 1 diabetes can increase the risk of developing microvascular disease, affecting the eyes, kidneys or nerves, while Type 2 can increase the risk of macrovascular
complications such as heart attack and stroke.
say that what is needed is an unequivocal demonstration that macrovascular
disease would respond to tight glucose control in type 2 diabetes.
Long-term complications of T2DM can be microvascular or macrovascular
Diabetes accounts for more than 10 percent of healthcare expenditures due to the associated micro-vascular and macrovascular
Metformin has also been shown to have several beneficial effects on cardiovascular risk factors and it is the only oral antihyperglycaemic agent thus far associated with decreased macrovascular
outcomes in patients with diabetes.
Sixty-two contributed chapters (by about 120 authors) address teh historical and social context, normal physiology, the pathogenesis of diabetes, management and treatment, microvascular and macrovascular
complications, other complications, special groups, delivery and organization of care, and future directions.
Patients with depression and diabetes are more likely to have higher macrovascular
and microvascular complications (4) and higher mortality rates (7).
There was also a 25 percent higher risk of developing advanced macrovascular
complications, such as stroke or myocardial infarction (heart attack from a blood clot), compared with diabetes patients without depression.
Progressive Cost of Complications (over 30 years) 0-5 6-10 11-15 16-20 21-25 26-30 years years years years years years Neuropathy $500 900 1,000 1,000 800 524 Retinopathy $850 1,530 1,700 1,700 1,360 891 Nephopathy $1,050 1,890 2,100 2,100 1,680 1,100 Macrovascular
$4,250 6,530 1,700 5,200 4,160 2,725 Source: * www.
He said that although the degree of glycemia in diabetic patients is strongly related to the risk of microvascular complications, the relation of glycemia to macrovascular
disease in diabetes is more modest.