macroprolactinoma

macroprolactinoma

/mac·ro·pro·lac·ti·no·ma/ (-pro-lak″tĭ-no´mah) a prolactinoma more than 10 mm in diameter, usually associated with serum prolactin levels above 500 ng per mL.

macroprolactinoma

[-prōlak′tinō′mə]
a prolactin-secreting pituitary tumor more than 10 mm in diameter that causes serum prolactin levels higher than 500 ng/mL. Bromocriptine is used with some success to shrink tumor size before surgery. Frequent monitoring of endocrine status is indicated for the remainder of the patient's life after therapy.
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Patients with macroprolactinoma, who are on bromocriptine or cabergoline, should continue their medication during pregnancy.
Hallazgos de la RM de acuerdo con los valores de prolactina * Nivel de RM Microprolactinoma prolactina normal (ng/mL) 25-50 8 14 51-100 7 6 101-200 3 2 201 o mas 0 1 Total 18 23 Nivel de Macroprolactinoma Otros prolactina hallazgos (ng/mL) 25-50 0 1 51-100 0 0 101-200 3 0 201 o mas 0 0 Total 3 1 * Una paciente tenia aracnoidocele Tabla 4.
in osteogenesis imperfecta), dorsolateral brainstem infarction, HIV infection, prolactin-secreting pituitary adenoma, cerebellopontine angle astrocytoma, leiomyosarcoma of the venous sinus, extracranial intraorbital cystic tumor, neurofibromatosis type 2, intracranial intraorbital metastasis, or invasion of the cavernous sinus by macroprolactinoma [8].
Fibroadenoma of the axilla in a patient with macroprolactinoma.
Spinal epidural lipomatosis associated with pituitary macroprolactinoma.
There are case series and case reports in the literature about patients who have been operated for craniopharyngioma (18-20) and one case for macroprolactinoma (21) who have developed adipsic DI.
In the absence of pregnancy and breast-feeding, a serum PRL level of >600 ng/mL is highly suggestive of a macroprolactinoma.
Treatment of macroprolactinoma with cabergoline: a study of 85 patients.
g, This man presented with 48 hours of bitemporal visual changes and was found to have a large mass compressing the optic chiasm, prompting rapid surgical removal; some macroprolactinomas in males may present with apoplexy, as did this patient's, and in some cases, endocrinologic test results are not known prior to surgery.
Surgical results in macroprolactinomas are much poorer, mainly in big and/or invasive tumors.
High prolactin levels may be missed by immunoradiometric assay in patients with macroprolactinomas.