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Related to macrophages: Natural killer cells, Dendritic cells


White blood cells whose job is to destroy invading microorganisms. Listeria monocytogenes avoids being killed and can multiply within the macrophage.
Mentioned in: Listeriosis

macrophages (ma·krō·fāˑ·jz), white blood cells (activated monocytes) that protect the body against infection and foreign substances by breaking them down into antigenic peptides recognized by circulating T cells.
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Clare Doris, Chief Operating Officer (COO) at Aquila BioMedical, said We are delighted to announce our partnership with Macrophage Pharma.
Macrophages from these peritoneal exudates were separated by method described (Liu et al; Lahat et al.
This is the first report demonstrating that tissue macrophages can be infected and that they respond to antiretroviral therapy,' Honeycutt said.
We knew that SAMHD1 is switched off when cells multiply, but macrophages do not multiply so it seemed unlikely that SAMHD1 would be switched off in these cells," Gupta wrote.
Macrophage Pharma was founded by the CRT Pioneer Fund to discover and develop novel therapies designed to enhance anti-tumour immune responses.
To correlate the reactive background cells, mast cells, and macrophages with B symptoms and stage of the disease.
5-50 [micro]M) of ADDA concentration-dependently inhibited expression/ release of inflammatory mediators (COX-2, iNOS, and NO), suppressed Akt and c-jun N-terminal kinase 1/2 (JNK) phosphorylation, and NF-[kappa] B activation in LPS-stimulated macrophages.
Macrophages are the immune system's first line of defense against TB when it first enters the body.
BCG-induced activation of macrophages has been associated with TNF production which is a critical cytokine in host defense mechanisms against mycobacterial infection [22].
Classically activated M1 macrophages are characterized by its high microbicidal function associated with the ability to secrete high amount of proinflammatory cytokines such as interleukin-1[beta] (IL-1[beta]), IL-12, tumor necrosis factor-[alpha] (TNF-[alpha]), and superoxide anions.
Once macrophages subsume the damaged mitochondria, the macrophages are able to repurpose the mitochondria for their own use, replenishing their own energy supplies.