macrophage inhibitory cytokine 1

macrophage inhibitory cytokine 1

a member of the transforming growth factor β superfamily, this has Th2-type cytokine actions. It is strongly localized to the maternofetal interface and may play a role in favoring viability.
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8 August 2014 - Chinese research, appearing today in the journal BMC Cancer, has demonstrated that macrophage inhibitory cytokine 1 (MIC-1/GDF15) may be a new diagnostic serum biomarker in early detection and postoperative monitoring of pancreatic ductal adenocarcinoma (PDAC).
Macrophage inhibitory cytokine 1 reduces cell adhesion and induces apoptosis in prostate cancer cells.
Serum concentrations of macrophage inhibitory cytokine 1 (MIC 1) as a predictor of miscarriage.
Researchers from Monash University, Victoria, Australia, report that decreased levels of macrophage inhibitory cytokine 1 (MIC1) early in pregnancy are associated with an increased risk of miscarriage.

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