macrophage activation

macrophage activation

The array of processes that upregulate macrophage activity.
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'In one trial, we gave haptoglobin to our model anemic mice before transfusing them and blocked macrophage activation, so they did not develop NEC-like symptoms,' Maheshwari says.
The Johns Hopkins University - New Mouse Model Yields Clues to Cause of Devastating Gut Disease in Premature Babies and Suggests Treatments
Curcumin alleviates macrophage activation and lung inflammation induced by influenza virus infection through inhibiting the NF-KB signaling pathway.
In Vitro Macrophage Nitric Oxide and Interleukin-1 Beta Suppression by Moringa peregrina Seed/Moringa peregrina Tohumlariyla In Vitro Makrofaj Nitrik Oksit ve Interlokin-1 Beta Baskilanmasi
Hypercytokinemia accompanied by severe clinical disease seen in EVD is reminiscent of what has been described for macrophage activation syndrome (MAS) and hemophagocytic lymphohistiocytosis (HLH).
Macrophage Activation Marker Soluble CD163 Associated with Fatal and Severe Ebola Virus Disease in Humans
Transcriptome-based network analysis reveals a spectrum model of human macrophage activation. Immunity 2014;40:274-88.
Research Trends of Macrophage Polarization: A Bibliometric Analysis
Lazar's team found that the TZDs, working through PPAR gamma, promote the metabolism of an amino acid called glutamine, a protein building block necessary for macrophage activation.
Diabetes drugs help immune cells in controlling inflammation
Macrophage activation syndrome following initiation of etanercept in a child with systemic onset juvenile rheumatoid arthritis.
Disseminated infection to immune activation
It carries severe morbidity of the joints and mortality when persistent systemic features leading to macrophage activation syndrome in some cases.
OUTCOME OF TOCILIZUMAB THERAPY IN CHILDREN WITH SYSTEMIC-ONSET JUVENILE IDIOPATHIC ARTHRITIS
Macrophage activation syndrome (MAS) is a potentially fatal complication of systemic juvenile idiopathic arthritis (sJIA), caused by an exaggerated but ineffective immune response involving excessive macrophage and T cell activation, followed by high production of proinflammatory cytokines (1-3).
COMPARISON OF DIFFERENT DIAGNOSTIC GUIDELINES FOR THE DIAGNOSIS OF MACROPHAGE ACTIVATION SYNDROME COMPLICATING SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS: SINGLE CENTRE EXPERIENCE/USPOREDBA RAZLICITIH DIJAGNOSTICKIH SMJERNICA ZA DIJAGNOZU SINDROMA AKTIVACIJE MAKROFAGA KOJI KOMPLICIRA SISTEMSKI TIP JUVENILNOG IDIOPATSKOG ARTRITISA: ISKUSTVO JEDNOG CENTRA
The abundance of epithelioid macrophages and lymphocytes in the granulomas at 28 dpi, may indicate that at this stage the triggered immune response is TH1-type, as in this type of response occurs a strong activation of T lymphocytes, inducers of an intense macrophage activation.
HISTOLOGICAL ANALYSIS OF THE TEMPORAL INFLUX OF IMMUNE CELLS INTO HEPATIC GRANULOMAS INDUCED BY TAENIA PISIFORMIS IN RABBITS
His immunological studies focused on the mechanism of macrophage activation and GcMAF.
Globulin Component Macrophage Activating Factor (GcMAF) Immunotherapy
Macrophage activation and human immunodeficiency virus infection: HIV replication directs macrophages towards a proinflammatory phenotype while previous activation modulates macrophage susceptibility to infection and viral production.
Breast cancer and HIV
Nearly 10% of children with systemic lupus erythematosus (SLE) developed macrophage activation syndrome (MAS) at some point during a mean follow-up time of more than 3 years at one center, and most were concomitantly diagnosed with the syndrome.
Macrophage activation syndrome's impact in childhood

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