macrophage activation

macrophage activation

The array of processes that upregulate macrophage activity.
References in periodicals archive ?
a clinical stage biotechnology company developing novel therapies to treat fibrotic and inflammatory diseases, announced today the publication of collaborative research in the Journal of Allergy and Clinical Immunology entitled, "Serum amyloid P attenuates M2 macrophage activation and protects against fungal spore-induced allergic airway disease.
Recent studies from our group suggest that neopterin may provide more comprehensive information regarding risk of cardiovascular events than do CRP measurements, particularly when macrophage activation is implicated, as seen in rapid CAD progression (5) and atheromatous plaque disruption (3).
Immune functions down-regulated by TGF-[Beta] include the following: major histocompatibility complex and Fc receptor expression, some cytokine production, thymocyte proliferation, T- and B-cell proliferation, IgG and IgM production, IL-2 receptor expression, cytotoxic T-cell generation and function, lymphokine-activated killer and natural killer cell activation and function, macrophage activation, macrophage respiratory burst activity, neutrophil adhesion to endothelium, and hematopoiesis (13).
Regulation of interferon and Toll-like receptor signaling during macrophage activation by opposing feedforward and feedback inhibition mechanisms.
Cell stress proteins as modulators of bacteria-host interactions 141 Chaperonin 60 and macrophage activation
Macrophage activation is important to the progression of multiple diseases through the release of inflammatory mediators.
These findings are especially exciting because other research has recently shown the same differences in macrophage activation in humans," said Odegaard.
During macrophage activation, nuclear translocation of NF-[kappa]B is preceded by phosphorylation of IKK by NF-[kappa]B inducing kinase (NIK) (Kang et al.
1) "The Role of elf5A in Human Macrophage Activation and TLR4 Signaling"

Full browser ?