CLEC4D

(redirected from macrophage C-type lectin)

CLEC4D

A gene on chromosome 12p13.31 that encodes a C-type lectin domain protein which acts as an endocytic receptor. It is thought to be involved in antigen uptake at the site of infection, either clearing the antigen, or processing it and presenting it to T cells.
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References in periodicals archive ?
Tsuiji et al., "Human macrophage C-type lectin specific for galactose and N-acetylgalactosamine promotes filovirus entry," Journal of Virology, vol.
Irimura, "Molecular cloning and expression of cDNA encoding human macrophage C-type lectin: its unique carbohydrate binding specificity for Tn antigen," Journal of Immunology, vol.

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