macrolide


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macrolide

 [mak´ro-līd]
1. a chemical compound characterized by a large lactone ring containing multiple keto and hydroxyl groups.
2. any of a group of antibacterial antibiotics containing such a ring linked to one or more sugars.

mac·ro·lide

(mak'rō-līd),
A natural lactone with a large ring; usually consisting of 14-20 atoms; macrolides include a class of antibiotics discovered in streptomycetes, for example, erythromycin; macrolides also inhibit protein biosynthesis.

macrolide

/mac·ro·lide/ (mak´ro-līd)
1. a compound characterized by a large lactone ring with multiple keto and hydroxyl groups.
2. any of a group of antibiotics containing this ring linked to one or more sugars, produced by certain species of Streptomyces.

macrolide

(măk′rō-līd)
n.
A class of antibiotics that are produced by certain actinomycetes of the genus Streptomyces, are characterized by a large lactone ring linked to one or more sugars, and act by inhibiting protein synthesis.

macrolide

A natural lactone with a large (14–20) carbon ring structure that inhibits protein synthesis; e.g., erythromycin.

mac·ro·lide

(mak'rō-līd)
A natural lactone, with a large ring, usually of 14-20 atoms; several antibiotics, including erythromycin, are macrolides. They inhibit protein biosynthesis.

macrolide

One of a range of antibiotics with a wide spectrum of action that can be used as an alternative to the penicillins to treat respiratory infections including LEGIONNAIRES' DISEASE. The group includes erythromycin, azithromycin and clarithromycin.

macrolide

as in antibiotic; any antibiotic with molecules having many-membered lactone rings, e.g. erythromycin, spiramycin, tylosin.
References in periodicals archive ?
Therefore, it is imperative that they be familiar with the drug interactions associated with the macrolide antibiotics.
Regarding macrolide resistance, 38 of 221 patients (17.
These findings, together with the slightly longer length of hospital stay with [macrolide monotherapy], reported associations with the development of resistance, and possible increased risk of cardiac events, indicate that the addition of macrolides for empirical treatment of CAP should be reconsidered," Dr.
Macrolide monotherapy was associated with a negative clinical response (OR, 0.
From the results it showed that newer macrolide antibiotics also found to have anti-inflammatory action which are in supportive with study conducted by Angela Ianaro et al in 2000.
If you have a heart or lung condition and are prescribed a macrolide for a respiratory infection, don't hesitate to remind your doctor that a different antibiotic might be safer for you.
Hahn states, patients on azithromycin were less likely to become colonized with bacteria, but when they did, the organisms were more likely to be macrolide resistant.
pneumoniae (without excluding HIV-infected patients) and demonstrated a lower mortality during the hospital stay in the group that received beta-lactam plus macrolide (p = 0.
Macrolides were used as the reference group in all analyses because these antibiotics and fluoro-quinolones are prescribed for similar community-acquired infections but macrolides do not directly influence glycemic control.
The system was evaluated following an outbreak of pertussis in a small institutional setting in a rural county by comparing the county's CUSUM signals for prescriptions for macrolide antibiotics with the onset of the outbreak.
Researchers say the macrolide class of drugs stands out among established antibiotics with a significant potential to yield a tuberculosis drug.