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1. a chemical compound characterized by a large lactone ring containing multiple keto and hydroxyl groups.
2. any of a group of antibacterial antibiotics containing such a ring linked to one or more sugars.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
A natural lactone with a large ring; usually consisting of 14-20 atoms; macrolides include a class of antibiotics discovered in streptomycetes, for example, erythromycin; macrolides also inhibit protein biosynthesis.
Farlex Partner Medical Dictionary © Farlex 2012
A class of antibiotics that are produced by certain actinomycetes of the genus Streptomyces, are characterized by a large lactone ring linked to one or more sugars, and act by inhibiting protein synthesis.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
macrolideA natural lactone with a large (14–20) carbon ring structure that inhibits protein synthesis; e.g., erythromycin.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
A natural lactone, with a large ring, usually of 14-20 atoms; several antibiotics, including erythromycin, are macrolides. They inhibit protein biosynthesis.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
macrolideOne of a range of antibiotics with a wide spectrum of action that can be used as an alternative to the penicillins to treat respiratory infections including LEGIONNAIRES' DISEASE. The group includes erythromycin, azithromycin and clarithromycin.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005