macrocytosis


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Related to macrocytosis: hypochromia

macrocythemia

 [mak″ro-si-the´me-ah]
the presence of macrocytes in the blood, as in macrocytic anemia and some types of liver disease. Called also macrocytosis.

mac·ro·cy·the·mi·a

(mak'rō-sī-thē'mē-ă),
The occurrence of unusually large numbers of macrocytes in the circulating blood.
[macrocyte + G. haima, blood]

macrocytosis

(măk′rō-sī-tō′sĭs)
n. pl. macrocyto·ses (-sēz)
The presence of macrocytes in the blood.

mac′ro·cy·tot′ic (-tŏt′ĭk) adj.

macrocytosis

The presence of abundant red cells/erythrocytes with a mean cell volume of > 100–105 fL. Macrocytosis is normal in newborns and infants but uncommon in adults, and is typical of vitamin B12 or folate deficiency.

macrocytosis

Hematology The presence of abundant RBCs with an MCV of > 105 fL and a diameter of ≥ 8.5 µm; macrocytosis is normal in newborns and infants, but uncommon in adults, and is typical of vitamin B12 or folate deficiency. See Megaloblastic anemia. Cf Microcystosis.

mac·ro·cy·the·mi·a

(mak'rō-sī-thē'mē-ă)
The occurrence of unusually large numbers of macrocytes in the circulating blood.
Synonym(s): macrocytosis, macrocythaemia.
[macrocyte + G. haima, blood]

macrocytosis

The condition in which the blood contains large numbers of enlarged red blood cells (macrocytes). This occurs when red cells are being produced more rapidly than normal to try to compensate for reduced oxygen carrying capacity.
References in periodicals archive ?
A total of 138 (3.7%) had macrocytosis, with 128 of these patients having charts that could be reviewed.
Categories of Mean Corpuscular Volume and Associated causes of Anaemia Category Mean Corpuscular Possible causes of Volume Anaemia Iron deficiency, Gastrointestinal Microcytosis < 81 fL with small bleeding, red blood cells Thalassaemia, Anaemia of chronic inflammation Iron deficiency, Gastrointestinal Normal Range 81-100 fL bleeding, Thalassaemia, Anaemia of chronic inflammation B12/ folate deficiency, >100 fL with large drug effect, Macrocytosis red blood cells Alcohol abuse, Myelodysplasia, Liver or thyroid disease Peripheral Smear Examination
Neuropsychiatry disorders caused by cobalamin deficiency in the absence of anemia or macrocytosis. N Engl J Med.
Savage et al., "Neuropsychiatric disorders caused by cobalamin deficiency in the absence of anemia or macrocytosis," New England Journal of Medicine, vol.
demonstrated in a population-based study among older from Finland that the presence of macrocytosis or macrocytic anemia did not increase the odds of having vitamin [B.sub.12] deficiency, which is consistent with the present results [34].
Also, the presence of macrocytosis together with a low reticulocytes number and increased BM apoptosis in Tfr2 KO mice resembles the erythropoiesis of myelodysplastic syndromes (MDS) [29].
Megaloblastic anemia and other causes of macrocytosis. Clin Med Res 2006; 4: 236-41.
Among these, a number of previous studies have reported that eiythrocyte macrocytosis, which refers to a high level of MCV, was exhibited in the disorder (Wachtel and Pueschel, I99I; David et al., 1996; Kivivuori et al., 1996; Dixon et al., 2010; Tenenbaum et aL, 20II).
Increase in red cell diameter above normal is called macrocytosis. Red cell sizes form a basis for morphologic or cytometric classification of anaemia [28].
Vegans are at a significant risk of vitamin [B.sub.12] deficiency (3) which can lead to macrocytosis, anemia, and decreased energy.
(9,10) Red blood cell size can easily be determined through dark field microscopy, with small cells (microcytosis) indicative of iron deficiency and large cells (macrocytosis) of vitamin B12 or folate deficiency.