macrocytic anaemia


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macrocytic anaemia

Anaemia characterised by macrocytic red blood cells, usually due to a discordance between maturation of the cytoplasm and nucleus typical of vitamin B12 or folate deficiency.

macrocytic anaemia

Anaemia in which the red blood cells are unusually large, as in PERNICIOUS ANAEMIA.
References in periodicals archive ?
Since macrocytosis is the earliest finding seen in patients with folate or vitamin B12 deficiency in most cases the classic expression of vitamin B12 deficiency is a macrocytic anaemia with accompanying elevated MCV.
There were elevated levels of folic acid in patients with macrocytic anaemia which was statistically significant.
Serum B12 deficiency can occur without Macrocytic anaemia and blood changes as patients with neurological deficits due to vitamin B12 deficiency have absent haemotogical features.
Other causes of Macrocytic anaemia are alcohol abuse, certain inherited disorders, drugs that affect DNA, such as chemotherapy drugs, leukaemia, Myelodysplastic syndrome, and myelofibrosis.
Macrocytic anaemia is often attributed to deficiencies in Vitamin [B.
Since alcoholism affects at least 30% of our country's population, it may be estimated that individuals, especially in the productive age group are affected by macrocytic anaemia and have a suppressed immune system.
In the USA and other high-income countries, the majority of folate tests are done to investigate macrocytic anaemia in non-pregnant patients.
Decreased absorption and dietary deficiency were found to be the cause of macrocytic anaemia (16%) (Figure 1).
Macrocytic anaemia describes as an anaemic state characterized by the presence of abnormally large RBC's in the peripheral blood.
Clinical evaluation of severe anaemia in pregnancy with special reference to macrocytic anaemia.
The incidence of macrocytic anaemia varied from 0-33.
It was also found out that majority of the subjects of mild anaemia (79%) had normocytic anaemia while in severe anaemia 31 % had microcytic anaemia, 31 % dimorphic and 26 % macrocytic anaemia.