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Benzimidazole (Oxfendazole), Imidazothiazole (Levamisole) and Macrocyclic lactones (Ivermectin) available in the market were determined by Fecal Egg Count Reduction Test (FECRT).
Objective: The macrocyclic lactones such as ivermectin are the cornerstone for the treatment of key nematode infections of livestock, crops and man.
2008), but their assemblages are threatened by the macrocyclic lactones (ML) used to treat endo- and ectoparasites in cattle (Floate, 2011).
The use of chemical anthelmintics is as old as the 1950s when 1st generation broad spectrum anthelmintics including phenothiazine and piperazine were produced after that with the passage of time more advanced and effective anthelmintics evolved as in 1960s containing 2nd generation anthelmintics like imidazothiazoles, benzimidazoles, pro benzimidazoles and tetra-hydro-pyrimidines were produced while in the 1980s a 3rd generation broad spectrum anthelmintics including macrocyclic lactones (Avermectins) have been produced which are still functional and being used by the veterinarians and livestock producers either in the form of injectable or drenching the animals like sheep, goat and cattle etc.
Heartworms, macrocyclic lactones, and the specter of resistance to prevention in the United States.
immitis resistance to macrocyclic lactones, such as ivermectin, for heartworm chemoprophylaxis.
Macrocyclic lactones derived from the fermentation of Streptomyces actinomycete bacteria.
The new product is effective against strains of parasites resistant to benzimidazoles, levamisole, macrocyclic lactones and combinations of these.
A joint statement released afterward announced, "This meeting was convened to discuss the implications of reports of lack of efficacy of macrocyclic lactones [preventive medications] against Dirofilaria immitis, the canine heartworm.
In Venezuela, the antihelmintic efficacy of different drugs have been evaluated, showing a good efficacy to the macrocyclic lactones and the benzimidazoles [11, 13].
There are plans to publish human health group summaries on Alcohol Branched Chain Saturated; Macrocyclic Ketones, Macrocyclic Lactones and Lactides, Aryl Alkyl Alcohols and Aryl Alkyl Alcohol Simple Acid Esters.