macrocyclic


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Related to macrocyclic: macrocyclic lactones, Macrocyclic compounds

macrocyclic

(mak″rō-sik′lik) [ macro- + cyclic]
Composed of two or more linked, ring-shaped chemical structures.
References in periodicals archive ?
Ipomoeassins A-E, cytotoxic macrocyclic glycoresins from the leaves of Ipomoea squamosa from the Suriname rainforest.
Roridin-A IgG antibodies, generated in animals, have been shown to be specific for macrocyclic tricothecenes (roridin is a type of macrocyclic tricothecene) (10).
Ian Paterson described the synthesis of complex acyclic and macrocyclic polypropionate derived-natural products based on optimized strategies for stereoselective formation of syn-syn and anti-syn aldol adducts using tin and boron enolates.
Forty sections treat ligand whose donor atoms come from a single group in the priodic table, ligands with mixed donors, and multidentate macrocyclic ligands.
We are pleased to join forces with Genentech, a universally-recognized leader in drug discovery and development, to further exploit Ensemble's unique macrocyclic drug discovery capability," said Dr.
By bringing together the power of solid phase methods (split and pool) and the novel chemistry enabled by the enzymes, we will generate highly diverse macrocyclic scaffolds containing amino acids, enzymatically modified amino acids, non-natural amino acids and non-amino acid building blocks.
There is extensive material on the distinctive features of the molecular and structural organization of biomolecules in solids and in solution and the structure of their inclusion complexes with different low-molecular, macrocyclic, and macromolecular substances.
Syntheses centre on macrocyclic ligands of the crown ether or cryptand type and related complexing agents.
As per the agreement, PeptiDream will identify macrocyclic peptides as potential drug candidates for disease targets being pursued by Lilly.
Dotarem -- which has been commercialized widely throughout the world since 1989 and more than 37 million doses administered[1] -- is the only macrocyclic and ionic GBCA.
The DESyne BD System comprises a cobalt chromium alloy stent, a proprietary technology to incorporate an ultrathin (<3 microns) biodegradable polylactide-based polymer coating, and Elixir's novel macrocyclic lactone compound Novolimus, eliminating the need for a primer layer.