macroalbuminuria

macroalbuminuria

(mak´rōalbū´-mənur´ēə),
n a type of albuminaria that is characterized by especially high levels of albumin in the urine (more than 300 mg in 1 day). This condition can be a symptom of many kidney diseases and disorders because its presence indicates that the kidney is leaking albumin (a protein found in blood). Also known as
proteinuria.
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References in periodicals archive ?
18 In diabetic patients, serum uric acid early in the course of diabetes is significantly correlated with later development of persistent macroalbuminuria.
The people having normal range ACR (<30 mg/g) were placed in the normo-albuminuria group, those having ACR in the range of 30-300 mg/g in micro albuminuria group and those having ACR more than 300 mg/g were placed in the macroalbuminuria group.
12) They confirmed that progressive renal function decline often preceded the appearance of macroalbuminuria or microalbuminuria in type 1 diabetic patients.
In normotensive patients with type 1 and type 2 diabetes, ACE inhibitor therapy reduces the risk of developing diabetic kidney disease, defined as new-onset microalbuminuria or macroalbuminuria, by 18% (strength of recommendation [SOR]: C, meta-analysis of randomized controlled trials [RCTs], disease-oriented evidence).
2] respectively, corresponding to 91% clients having macroalbuminuria (ACR >30 mg/mmol), and 15% having an eGFR <30 ml/min/1.
According to the American Diabetic Association classification of microalbuminuria, patients were divided into three groups: normal albumin group, spot UACR <30 mg/g*Cr; microalbuminuria, spot UACR 30–299 mg/g*Cr; and macroalbuminuria, spot UACR ≥300 mg/g*Cr.
Low 25-hydroxyvitamin D2and 25-hydroxy vitamin D3 levels are independently associated with macroalbuminuria, but not with retinopathy and macrovascular disease in type 1 diabetes: the EURODIAB prospective complication study.
Mann said: 20% had a moderate renal impairment at baseline, 20% had microalbuminuria, and 5% had macroalbuminuria.
Exclusion criteria included other anti-diabetic drugs, beta-blocker use, blood pressure >160/100 mmHg, macroalbuminuria, heart disease and smokers.
A normal urinary albumin/creatinine ratio was defined as <3 mg/mmol, microalbuminuria as a urine albumin level of 3-30 mg/mmol, and macroalbuminuria as >30 mg/mmol.