mRNA


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Related to mRNA: tRNA, rRNA

mRNA

 
messenger RNA; see ribonucleic acid.

mRNA

Abbreviation for messenger RNA. See entries under ribonucleic acid

mRNA

abbr.
messenger RNA

messenger RNA

An RNA (ribonucleic acid) molecule which has coding regions and translation signals derived from a gene, carries the reverse template message from DNA, and is required for protein synthesis. mRNA is a nucleic acid intermediate that specifies the amino acid sequence of a polypeptide during translation. Under most circumstances, and in accordance with the so-called central dogma of biology, the message flows from DNA to RNA, which is then translated into protein. DNA is wrapped around proteins (histones in chromatin); the DNA then unwinds, allowing transcription by one of the three RNA polymerases, forming a primary (nuclear) RNA transcript that is then processed to remove the intervening RNA sequences (introns), yielding a mature mRNA molecule. The mature mRNA then passes through nuclear pores into the cytoplasm, where translation into proteins occurs. When a particular mRNA is no longer needed, it is degraded by ribonucleases.

mRNA

Abbreviation for messenger RNA.

mRNA

see MESSENGER RNA.
References in periodicals archive ?
According to Tables 2 and 3, for the muscle, pancreatic secretion pathway (bta04972) and biological process (BP) term of anterior/posterior pattern specification (BP_GO:0009952) are uniquely found for the mRNA only pipeline.
Because mRNA can be easily broken down in the body, it needs to transported within some kind of protective carrier.
A 7-methyl-guanosine at their 5' ends (5' cap) is another important structure for the expression and the stability of mRNA in cell cytoplasm when mRNA leaves the nucleus.
51) Although the activation of TLR signaling pathways is normal, the decay of Il-6 mRNA is impaired in [Regnase-1.sup.-/-] macrophages.
For evaluating our methods, we compare performance in terms of statistical significances between a significant 317 mRNA cluster and randomly simulated 10,000 clusters.
AATD Hepatocytes were transfected with 4ul of Lipofectamine[R] 2000 (Thermo Fisher Scientific, Inc., Waltham, MA) per 2.5ug mRNA, in 3 independent experiments with 3 biological replicates per experiment.
Results: SIRT3 mRNA expression was higher in the RA group than in the healthy control group (4.64 fold, p<0.001), whereas SIRT2 mRNA expression was relatively lower in the RA group than in the healthy control group (0.55 fold, p=0.109).
Upregulation of the mRNA of catalase, an extensively investigated antioxidant, was confirmed by real-time RT-PCR and found to be 1.5 times higher in TM cells treated with Y-27632 compared to the control TM cells (P = 0.032; Figure 1(a)).
In this study, we sought to examine the differential regulation of RAS isoforms at mRNA level in cutaneous melanoma.
The team knew that mRNA was shipped in a controlled fashion to the endfeet, rather than merely diffusing, but they didn't know which other molecules might control these steps.
The underlying explanation for improved specificity is detection of mRNA encoding E6 and E7 oncogenic proteins indicating lesion progression to invasive cancer.