BCL10

(redirected from mE10)

BCL10

A gene on chromosome 1p22 that encodes a protein which contains a caspase recruitment domain (CARD); it induces apoptosis, activates NF-kappaB and interacts with other CARD domain proteins (e.g., CARD9, 10, 11 and 14), which are thought to act as upstream regulators in NF-kappaB signalling.

Molecular pathology
BCL10 protein product forms a complex with MALT1, a protein encoded by a gene that is translocated in MALT lymphoma and together activate NF-kappaB; deregulation of either BCL10 or MALT1 may lead to MALToma.

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Capabilities also include Mold Design, OneSpace Designer, ME10 Dynamic Drafting, and Design Data Management (as described above).

Collaborate on design, cut turnaround times. (Computer Hardware & Software)

The software selected by MGCS was SolidDesigner from CoCreate, Fort Collins, CO, which provided continuity from MGCS' existing 2D package, CoCreate's ME10.

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The first of these ports is scheduled for later this year when ME10 and HP-DPM are made available on Sparestations from Sun Microsystems Inc.