(12,14) There is also a reduction in the number of L- and M-cone
cells due to phagocytosis of cone cells by RPE cells and as a result of the NR2E3 gene mutation.
 were used: [beta]-actin, forward 5'-GACGAAGCCCAGAGCAAA-3', reverse 5'-CCAG AGGCATACAGGGACAG-3'; S-cone, forward 5'-GAGT ATTTCGCCTGGTTCCTT-3', reverse 5'-CCTTCTGGGTT GTAGCTGATT-3'; M-cone, forward 5'-TCATCGCATCC ATCTTTACCA-3', reverse 5'-AGCACGAAGTAGCCGT AGACC-3'.
After calculating the protein concentrations, samples (30 [micro]g) were electrophoresed and subjected to Western blotting using S-cone and M-cone antibodies.
The transitional zone between these two retinal areas is populated by coexpressing cones that express both S-cone and M-cone photopigments .
Our study also indicated that, compared with the WL group, the S-cone density increased and the M-cone density decreased in the dorsal and ventral retinas of the SL group, while the reverse was true of the ML group.
The increase in S-cone and M-cone densities led to an increase in S-opsin and M-opsin expressions and vice versa.
The other type of red-green color deficiency, known as deuteranomaly, affects the M-cone
and indicates a green weakness.
(32) The gene that codes for the S-cone pigment is found on chromosome 7 and those encoding the L- and M-cone pigments are located on the X-chromosome.
The S-cone pigment gene has 348 codons and shows a 46 [+ or -] 1% similarity to either the L- or M-cone pigment gene.
Firstly, the L- and M-cone opsin genes are polymorphic.
(32,37) Most studies indicate that one L-cone opsin gene is found at the beginning of the array, and is followed by one or more M-cone or hybrid opsin genes.
The L- and M-cone sensitivities used to construct this diagram summate to the photopic luminosity function, whereas the S-cone sensitivities are scaled in any convenient way, although most frequently so that the maximum b value is 1.