lysosome

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lysosome

 [li´so-sōm]
one of the minute bodies occurring in many types of cells, containing various hydrolytic enzymes and normally involved in the process of localized intracellular digestion. adj., adj lysoso´mal.

ly·so·some

(lī'sō-sōm),
A cytoplasmic membrane-bound vesicle measuring 5-8 nm (primary lysosome) and containing a wide variety of glycoprotein hydrolytic enzymes active at an acid pH; serves to digest exogenous material, such as bacteria, as well as effete organelles of the cells.
[lyso- + G. soma, body]

lysosome

/ly·so·some/ (li´so-sōm) one of the minute bodies occurring in many types of cells, containing various hydrolytic enzymes and normally involved in the process of localized intracellular digestion.lysoso´mal
secondary lysosome  one that has fused with a phagosome (or pinosome), bringing hydrolases in contact with the ingested material and resulting in digestion of the material.

lysosome

(lī′sə-sōm′)
n.
A membrane-bound organelle in the cytoplasm of most cells containing various hydrolytic enzymes that function in intracellular digestion.

ly′so·so′mal adj.

lysosome

[lī′səsōm]
Etymology: Gk, lysein + soma, body
a cytoplasmic, membrane-bound particle that contains hydrolytic enzymes that function in intracellular digestive processes. The organelles are found in most cells but are particularly prominent in leukocytes and the cells of the liver and kidney. If the hydrolytic enzymes are released into the cytoplasm, they cause self-digestion of the cell. Thus lysosomes may play an important role in certain self-destructive diseases characterized by the wasting of tissue, such as muscular dystrophy.

ly·so·some

(lī'sō-sōm)
A cytoplasmic membrane-bound vesicle measuring 5-8 nm (primary lysosome) and containing a wide variety of glycoprotein hydrolytic enzymes active at an acid pH; serves to digest exogenous material, such as bacteria, as well as effete organelles of the cells.
[lyso- + G. soma, body]

lysosome

One of the types of ORGANELLE found in cell cytoplasm. Lysosomes contain various hydrolytic enzymes capable of digesting large molecules (macromolecules), the products of which can then leave the lysosomes. Injury to lysosomes may release enzymes that can damage the cell.

lysosome

a cytoplasmic organelle of EUKARYOTE cells that contains hydrolytic enzymes and is thought to be produced by the GOLGI APPARATUS. The sac-like structure is surrounded by a single-layered membrane which is impermeable and resistant to the enzymes inside. Lysosomes can act as the digestive system of the cell. When the sac ruptures the enzymes are released into a food vacuole produced by PHAGOCYTOSIS, thus enabling the breakdown of ingested materials.

Lysosome

Membrane-enclosed compartment in cells, containing many hydrolytic enzymes; where large molecules and cellular components are broken down.
Mentioned in: Mucopolysaccharidoses

ly·so·some

(lī'sō-sōm)
A cytoplasmic membrane-bound vesicle (primary lysosome) and containing a wide variety of glycoprotein hydrolytic enzymes active at an acid pH; serves to digest exogenous material, such as bacteria.
[lyso- + G. soma, body]

lysosome

a small intracellular organelle occurring in the cytoplasm of most cells, containing various hydrolytic enzymes and normally involved in the process of localized intracellular digestion. Lysosomes are particularly prominent in certain cells such as granulocytes, in which they are the granules, and activated macrophages. They play a major role in intracellular killing of microorganisms, destruction of foreign or damaged tissues, and in embryogenesis.
References in periodicals archive ?
20],[21] This may be due to the accumulation of lysosomes and autophagolysosomes in neurites or glial cells around amyloid plaques.
Brucella suis-impaired specific recognition of phagosomes by lysosomes due to phagosomal membrane modifications.
In alternative macroautophagy, autophagic membranes are generated from Golgi-derived thick membranes, and thus can easily fuse with the thick membranes of lysosomes.
And as with Alzheimer's, the poor function and acidification of lysosomes has been implicated in these disorders as well.
The researchers developed a strategy to deliver HP-beta-CD to lysosomes without affecting other cell structures.
In the next phase of their study, the researchers showed that clogging up the macrophages' lysosomes in the zebrafish with non-biological material - such as tiny plastic beads - has the same result.
The green fluorescent signal of Cyto-ID[R] is based on cytosolic compartments which can be specifically labeled with minimal staining of lysosomes and endosomes (Guo et al.
Over time, the amount of material building up in each lysosome causes it to swell and occupy more space in the cell, leading to additional problems for normal cellular function, said the experts addressing the session.
Keywords: Daphnia magna, gill epithelium, membrane infoldings, mitochondria, rough endoplasmic reticulum, dense tubules, multivesicular bodies, coated vesicles, cuticle, lysosomes
The homogenate was subjected to differential centrifugation for different fractions: (1) structural proteins, nucleus, and cell debris, 600 g, 10 min; (2) mitochondria, 5000 g, 10 min; (3) lysosomes, 15000 g, 10 min; (4) supernatant, cytosol.
Lysosomes act as a sort of recycling and disposal center for cells.
In hemocytes, one such parameter appears to be relative membrane stability, typically quantified by examining the capacity of lysosomes to retain Neutral Red dye.