lysophospholipase

ly·so·phos·pho·lip·ase

(lī'sō-fos'fō-lip'ās),
A hydrolase removing the single acyl group from a lysolecithin, producing glycerophosphocholine and the free fatty acid anion.
Synonym(s): lecithinase B, lysolecithinase, phospholipase B (1)
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References in periodicals archive ?
Autotaxin has lysophospholipase D activity that converts lysophosphatidylcholine (LPC) into LPA.
Bridge Biotherapeutics files IND for BBT-877 with US FDA for for treatment of Idiopathic Pulmonary Fibrosis
[6] GAL 13 was originally identified as 16-kDa protein with lysophospholipase activity named placental protein 13 (PP13).
Placental protein 13, galectin 14 and pentraxin 3 for prediction of preeclampsia in Egyptian patients
The lysophospholipase autotaxin and its product, lysophosphatic acid, have been shown to be increased in patients with pruritus due to cholestasis.
Albireo reports data on Pharmacodynamic Marker for A4250 in children with CLD
Another member of the family, ENPP2, also known as autotaxin, has been considered a secreted lysophospholipase D that is produced in adipocytes and is responsible for the synthesis of lysophosphatidic acid.
The hepatic ectonucleotide pyrophosphatase/phosphodiesterase 1 gene mRNA abundance is reduced by insulin and induced by dexamethasone
Said-Fernaandez, "Identification ofEntamoeba histolytica intracellular phospholipase A and lysophospholipase L1 activities," Parasitology Research, vol.
"CLUPS": A New Culture Medium for the Axenic Growth of Entamoeba histolytica
The organism is rich in phospholipases and lysophospholipase essential for cytolysis of cells [40].
Amoebic Liver Abscess and Indigenous Alcoholic Beverages in the Tropics
Among the seven members of this family, ATX is a unique enzyme that shows lysophospholipase D activity [17, 18].
Autotaxin-Lysophosphatidic Acid: From Inflammation to Cancer Development
Moreover, several enzymes in the [PLA.sub.2] family also catalyze the phospholipase [A.sub.1] ([PLA.sub.1]), lysophospholipase, neutral lipid lipase, or even transacylase/ acyltransferase reaction rather than or in addition to the genuine [PLA.sub.2] reaction.
Lipoquality control by phospholipase [A.sub.2] enzymes
(34.) Chen SC, Wright LC, Golding JC, Sorrell TC (2000) Purification and characterization of secretory phos-pholipase B, lysophospholipase and lysophospholipase/transacylase from a virulent strain of the pathogenic fungus Cryptococcus neoformans.
Impact of Enzymes and Toxins Potentiality of Four Aspergillus Species to Cause Aspergillosis
Austen, "Biochemical characterization of human eosinophil Charcot-Leyden crystal protein (lysophospholipase)," The Journal of Biological Chemistry, vol.
Tissue- and Condition-Specific Isoforms of Mammalian Cytochrome c Oxidase Subunits: From Function to Human Disease
Ben Gharsa et al., "The pathological effects of Heminecrolysin, a dermonecrotic toxin from Hemiscorpius lepturus scorpion venom are mediated through its lysophospholipase D activity," Toxicon, vol.
Scorpion Venom Active Polypeptide May Be a New External Drug of Diabetic Ulcer
GPC/E levels are the net result of several different enzyme activities including Phospholipase A2, group IV A/B, Lysophospholipase 1/2, Phospholipase B1, Phospholipase A2G3, Phospholipase A2G10, and Phospholipase A2G12A and their regulation is difficult to interpret [19].
Response Detection of Castrate-Resistant Prostate Cancer to Clinically Utilised and Novel Treatments by Monitoring Phospholipid Metabolism

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