Second reason of lymphopenia might be due to corticosteroid action as they cause redistribution of T-lymphocytes and lympholysis
A lymphopenia like condition in animal with periparturient inflammatory diseases may be associated with corticosteroid induced shifts of lymphocytes from blood to other body compartments or due to lympholysis
, especially of T cells as suggested by Jain (1993).
Furthermore, Jain (1993) reported that corticosteroid in induced lymphopenia attributed to lympholysis
in blood and lymphoid tissue, increased shift of lymphocytes from blood to other body compartments, or both.
Data from the study showed that FZD is effective at lowering viral load the first two weeks of FIV infection, and may also decrease early FIV-associated lympholysis