lymphoid follicle


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Related to lymphoid follicle: lymphoid tissue, Lymph system

lymphoid follicle

A densely-packed, spherical or ovoid aggregation of B lymphocytes that forms a lymphocyte proliferation and maturating zone in a lymphoid tissue, such as a lymph node.
Synonym: lymph follicle
See also: follicle
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
(1973) Pinocy tosis by epithelium associated with lymphoid follicles in the bursa of Fabricius, appendix, and Peyer's patches.
Morphologic Features of Eosinophilic Angiocentric Fibrosis (a) Frequent Occasional Early stage Eosinophilic vasculitis Early fibrosis Eosinophilic infiltrate Lymphoid follicles Lymphoplasmacytic infiltrate Late stage Loss of lymphoplasmacytic Residual lymphoid infiltrate follicles Prominent eosinophils Concentric angiocentric stromal fibrosis (onionskin) (a) Never seen (features that should prompt consideration of other entities): granulomas, necrosis, mitotic activity, cytologic atypia.
The [CD20.sup.+] B cells were principally situated at the central region of lymphoid follicles. Similar to pSS group with FS = 2, CD138+ plasma cells were also displayed as a scattered distribution outside the infiltrates; however, some of them were observed at the border of B cell zone as well.
Peribronchial lymphoid follicles are organised by lymphoid neogenesis [87] in T-cell and B-cell compartments through the lymphoid chemokines CCL19 and CCL21 and CXCL12 and CXCL13 [78, 88-90].
Histologic Features of the Lymphoid Interstitial Pneumonia-like Pattern (a) Major histologic features (b) Diffuse and alveolar septal distribution Extensive lymphoplasmacytic infiltration Focal alveolar wall destruction Eosinophilic exudate in the alveolar space Minor histologic features (c) Lymphoid follicle with or without germinal center Nonnecrotizing granuloma Cyst formation Rare histologic findings Severe architectural distortion Chronic dense fibrotic changes Distribution along lymphatic routes Organizing pneumonia Negative histologic findings Lack of neoplastic condition Lack of necrotizing granuloma (a) References: Travis et al, (1) Sirajuddin et al, (8) Kokosi et al, (9) and Hashisako et al.
Although the esophagus and stomach are not associated with prominent lymphoid tissue under normal conditions, the stomach can develop acquired mucosa-associated lymphoid tissue (MALT) under pathologic conditions, the prototypical example being the development of lymphoid follicles in response to Helicobacter pylori infection.
DISCUSSION: Kuttner tumour, otherwise known as chronic sclerosing sialadenitis, is a chronic inflammatory disease of the salivary gland characterised by progressive periductal fibrosis, dilated ducts with a dense lymphocyte infiltration and lymphoid follicle formation and acinar atrophy (1).
Also few atrophic acini are seen with areas of lymphoplasmocytic infiltrates and lymphoid follicle formation.
For the inflammatory components, we applied the scoring system to the eosinophilic (Figure 1, A through C) and lymphocytic (Figure 1, D through F) infiltrates, as well as the presence or absence of lymphoid follicle formation.
(6, 7) On the other hand, if UIP pattern is recognized, it should be specified if ancillary findings suggesting chronic hypersensitivity pneumonitis or collagen vascular disease or asbestosis (eg, chronic lymphoplasmacytic inflammation with or without lymphoid follicles, interstitial granulomas/giant cells, bronchiolitis, pleuritis, bridging fibrosis, asbestos fibers, eosinophilic infiltrate) are present or absent/minimal.