lymphocytic choriomeningitis virus


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lym·pho·cyt·ic cho·ri·o·men·in·gi·tis vi·rus

an RNA virus of the family Arenaviridae that infects mice, monkeys, dogs, and guinea pigs, and causes lymphocytic choriomeningitis; in humans, infection may be inapparent, but sometimes the virus causes influenzalike disease, meningitis, or rarely meningoencephalomyelitis; in utero infections of mice establish a type of immunologic tolerance.
Synonym(s): LCM virus
References in periodicals archive ?
A case of congenital lymphocytic choriomeningitis virus (LCMV) infection revealed by hydrops fetalis.
Lymphocytic choriomeningitis virus chorioretinitis mimicking ocular toxoplasmosis in two otherwise normal children.
Lymphocytic choriomeningitis virus (LCMV) and pregnancy: facts and prevention.
Laboratory studies of a lymphocytic choriomeningitis virus outbreak in man and laboratory animals.
Pathology of fatal lymphocytic choriomeningitis virus infection in multiple organ transplant recipients from a common donor.
High diversity and ancient common ancestry of lymphocytic choriomeningitis virus. Emerg Infect Dis.
Outbreak of lymphocytic choriomeningitis virus infections in medical center personnel.
Two epizootics of lymphocytic choriomeningitis virus occurring in laboratory mice despite intensive monitoring programs.
Thymus-dependent lymphocytes: destruction by lymphocytic choriomeningitis virus. Science.
Development of a reverse transcription-polymerase chain reaction assay for diagnosis of lymphocytic choriomeningitis virus infection and its use in a prospective surveillance study.
The synanthropic nature of some rodent species makes them important reservoirs of RNA viruses pathogenic to humans, such as hantaviruses (e.g., Seoul virus in black and Norway rats worldwide) and arenaviruses (e.g., Lassa virus in the multimammate mouse in western Africa or lymphocytic choriomeningitis virus in the house mouse worldwide).
Lymphocytic choriomeningitis virus (LCMV), an Old World arenavirus, family Arenaviridae, is a zoonotic virus maintained in the house mouse (Mus musculus) and can be carried by pet and laboratory rodents (1-7); human exposure occurs through aerosolized excreta or by direct rodent contact.