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Results demonstrated that vitamin B6 deficiency influenced the immune system in three ways: (1) downregulation of SOCS-1 expression, as well as upregulation of T-bet expression, (2) suppression of T lymphocyte differentiation, and (3) decreased levels of IL-2 secretion and increased levels of IL-4 secretion.
standard T lymphocyte differentiation assays) induced a dose-dependent release of TGF-AY.

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