If a surgeon must use PBD for lymphatic mapping
, a preoperative prophylaxis such as glucocorticoid or diphenhydramine is recommended.
Morton, "Lymphatic mapping
and sentinel lymphadenectomy for breast cancer," Annals of Surgery, vol.
Role for lymphatic mapping
and sentinel lymph node biopsy in patients with thick (= 4 mm) primary melanoma.
The trial did not evaluate enough patients with thin melanomas (less than 1.20 millimeters thick) to understand how they might benefit from lymphatic mapping
and sentinel-node biopsy.
with sentinel node approach is one of the most interesting recent developments in surgical oncology, allowing patients with metastasis to be treated in early phase without submitting other patients to unnecessary regional dissection.
Sentinel lymph node biopsy performed before the start of neoadjuvant chemotherapy eliminates any effects of chemotherapy on the technical aspects of lymphatic mapping
, such as lymphatic sclerosis in response to chemotherapy.
Chardonnens et al., "Intraoperative lymphatic mapping
and sentinel node biopsy using hysteroscopy in patients with endometrial cancer," Gynecologic Oncology, vol.
methylene blue) that can be used successfully for lymphatic mapping
where the incidence of allergic reactions is minimal?
and sentinel lymph node sampling in breast cancer: a meta-analysis (ASCO Annual Meeting Proceedings, Orlando, FL, 2002).
Other subjects covered are lymphatic mapping
and sentinel lymph node biopsy in early-sage cervical cancer, and the use of docetaxel labeled with radionuclide against cervical cancer cells in vitro.
and sentinel lymph node biopsy have significantly changed the initial approach to the patient with melanoma and have reinvigorated debate over the importance and management of regional lymph nodes in cutaneous malignant melanoma.
More than 5,200 patients participated in the Axillary Lymphatic Mapping
Against Nodal Axillary Clearance randomized multi-center trial (ALMANAC) in the United Kingdom.