aTyr is actively investigating NRP2 receptor biology, both internally and in collaboration with key academic thought leaders, to identify new product candidates for a variety of disease settings, including cancer, inflammation, and lymphangiogenesis
The Vascular Endothelial Growth Factor-A (VEGF-A) family has been shown to regulate angiogenesis and lymphangiogenesis
(Bates et al.; Adefolaju et al., 2017).
Lymphatic vessel density (LVD) refers to the number of lymphatic vessels per unit area.8 The increase of LVD is related to lymphangiogenesis
, while lymphangiogenesis
is closely related to lymph node metastasis.9 Lymph node metastasis is an important way of metastasis of gastric cancer and also one of the early events of gastric cancer metastasis.
This year's 26 articles cover cardiovascular physiology, cell physiology, endocrinology and metabolism, gastrointestinal physiology, neurophysiology, renal and electrolyte physiology, respiratory physiology, special topics: angiogenesis and lymphangiogenesis
, and general interest.
Opposing roles of JNK and p38 in lymphangiogenesis
New York, NY, November 22, 2018 --(PR.com)-- The research on "Sunitinib Stimulates Expression of VEGFC by Tumor Cells and Promotes Lymphangiogenesis
In Clear Cell Renal Cell Carcinomas" was conducted by Maeva Dufies, Sandy Giuliano, Gilles Pages and team.
Connective tissue growth factor regulates fibrosis-associated renal lymphangiogenesis
. Kidney Int 2017;92:850-63.
This Sema3C mutant also inhibited tumor lymphangiogenesis
and the metastatic spread of tumor cells to lymph nodes.
in inflammatory breast carcinoma: a histomorphometric study.
It promotes lymphangiogenesis
and stimulates lymphatic motility with no significant changes in the tissue architecture.
Lithium inhibits tumor lymphangiogenesis
and metastasis through the inhibition of TGFBIp expression in cancer cells.