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lymphadenopathy/lym·phad·e·nop·a·thy/ (-op´ah-the) disease of the lymph nodes.
lymphadenopathyA generic term for lymph node enlargement of any aetiology, benign or malignant.
• Viral—Infectious mononucleosis, CMV, HIV.
• Bacterial—Typhoid, TB, syphilis, Yersinia.
• Lymphoproliferative—especially lymphoma
Lipid storage, Niemann-Pick, sphingomyelia.
Phenytoin, allopurinol, isoniazid.
Automimmune, rheumatoid arthritis, sarcoid, GVHD.
Benign hyperplasia, Langerhans cell histiocytosis.
lymphadenopathyEnlarged lymph nodes, follicular hypertrophy, swollen lymph glands Hematology Enlargement of lymph nodes of any etiology; the differential diagnostic considerations are multiple and divided into reactive patterns; benign lymphadenopathy is characterized by
lymphadenopathy(lim″fad″ĕ-nop′ă-thē) [ lymph- + adenopathy]
Enlarged LNs may be tender or not; tenderness often is present when lymph nodes swell rapidly (e.g., in response to infections, hypersensitivity reactions, or some fulminant lymphomas). Rock-hard, enlarged, and immobile LNs are typical of metastatic cancer, whereas rubbery LNs are found in lymphomas. LNs that do not resolve spontaneously within 4 to 6 weeks, or for which no obvious explanation exists, usually are sampled by biopsy or aspiration.
|Category||Examples||Location||Age of patient||Texture||Size||Associated signs or symptoms||Diagnostic tests||Necessity for biopsy or aspirate|
|Bacterial infection||Strep throat; cat scratch disease||Angle of the jaw; axilla, neck||Child or preteen; any||Relatively soft and tender; relatively soft and tender||1 sq. cm; > 1 cm||Fever, sore throat, tonsillar exudate, malaise, headache, difficulty swallowing; may have fever, night sweats, weight loss||Can be diagnosed clinically; antibody blood tests||No; not usually|
|Granuloma||Tuberculosis; sarcoidosis||Neck, chest; hilum of the lung and other locations||Any; usually adults||Relatively soft and tender; rubbery||> 1 cm; > 1 cm, sometimes massive||May have fever, night sweats, weight loss, productive sputum; cough, shortness of breath, may have systemic illness, or be asymptomatic||Tuberculin (purified protein derivative), interferon blood test, sputum for acid-fast bacilli; blood for ACE levels||Occasionally; often|
|Metastatic cancer||Breast cancer||Axilla next to the breast||Adults||Stone||Especially likely if > 2 cm||Lump in the breast||Mammography, ultrasound, other imaging techniques||Yes|
|Lymphoma||Hodgkin lymphoma||Chest, neck, axilla, groin, or all of these||Young adult||Rubbery||> 1 cm||May have fever, night sweats, weight loss, enlarged spleen||Radiologic imaging||Yes|
|Viral infection||Mononucleosis; HIV/AIDS||Head and neck, spleen; generalized||Young adult; any, but most often young adult or adult||Rubbery; firm||About 1 cm; variable||May have fever, night sweats, weight loss; fever, night sweats, weight loss, or symptoms of opportunistic infection||Tests for Epstein-Barr virus, heterophile antibody; antibody blood tests||No; not usually|
lymphadenopathyAny disease process affecting a LYMPH NODE. Also known as lymphadenosis.
regional lymphadenopathytenderness, pain and swelling of regional lymph glands (e.g. popliteal or inguinal glands) indicative of proximal spread of distal infection, e.g. from the foot; usually associated with other signs of systemic infection, i.e. general malaise, pyrexia and fever and other constitutional symptoms
n a disease process that involves a lymph node or nodes.
Patient discussion about lymphadenopathy
Q. my friend ate a bar of chocolate and now her left neck gland is swollen any ideas why? no other symptoms
if it is an infection, you can usually find such other infection symptoms like : fever, pain in that swollen area, increased white blood cells (in blood work test), etc.
if it is an allergy, usually it will fade away itself in couple of days, or you can just try to consume anti-allergic drugs, such as : loratadine and maybe combined with dexamethasone.
Good luck, and stay healthy always..