lyase


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Related to lyase: Ligases, Isomerases

lyase

 [li´ās]
any of a class of enzymes that remove groups from their substrates (other than by hydrolysis), leaving double bonds, or that conversely add groups to double bonds.

ly·ase

(lī'ās),
Class name for those enzymes removing groups nonhydrolytically (EC class 4); prefixes such as "hydro-" and "ammonia-" are used to indicate the type of reaction. Trivial names for lyases include synthases, decarboxylases, aldolases, and dehydratases. Compare: synthase, synthetase.

lyase

/ly·ase/ (li´ās) any of a class of enzymes that remove groups from their substrates (other than by hydrolysis or oxidation), leaving double bonds, or that conversely add groups to double bonds.

lyase

(lī′ās′)
n.
Any of a group of enzymes that catalyze the cleavage of bonds without hydrolysis or oxidation, often resulting in a new double bond or ring structure, or that catalyze the addition of chemical groups to double bonds.

ly·ase

(lī'ās)
Class name for enzymes removing groups nonhydrolytically (EC class 4); prefixes such as "hydro-," and "ammonia-" are used to indicate the type of reaction. Trivial names for lyases include synthases, decarboxylases, aldolases, dehydratases.
Compare: synthase, synthetase

lyase

an enzyme that catalyses
  1. the addition of groups to double bonds,
  2. the removal of groups to form double bonds.

lyase

any of a class of enzymes that remove groups from their substrates (other than by hydrolysis), leaving double bonds, or that conversely add groups to double bonds.
References in periodicals archive ?
Our recent insights into the unique CYP17 lyase inhibition profile of galeterone have broadened our understanding of its novel triple mechanism of action and the related clinical observations in our ARMOR1 Phase 1 study," said Martin D.
Expression of cytochrome P450 17a-hydroxylase/C17-20 lyase in the fetal rat testis is reduced by maternal exposure to exogenous estrogens.
1-A Diffraction of Chorismate Lyase from Escherichia coil, J.
Like all proteins, pectate lyase C consists of a long string of amino acids with its own characteristic sequence.
Purification and characterization of pectin lyase from Rhizoctonia solani.
The key ingredient in Garcinia Cambogia is called Hydroxycitric Acid (HCA), which works in the body to inhibit the production of citrate lyase, an enzyme that the body utilizes to help turn carbohydrates into fat.
Increased citrulline indicates a deficiency in either argininosuccinate synthase or argininosuccinate lyase (1).
In this invention, several bathochromic phytochromes were generated by site-directed mutagenesis in the region of bilin lyase domain in plant PHYA, and their ability to suppress the shade avoidance reactions were examined by transforming the bathochromic phytochromes into PHYA deficient Arabidopsis thaliana (ecotype col-0).
Specific topics are thermodynamics of the dissociation of weak acids, apparent equilibrium constants, biochemical reactions at specific temperatures and pHs, the use of matrices, the binding of ligands by proteins, calorimetry, and oxidoreductase, transferase, hydrolase, and lyase reactions.
tuberculosis that lack the gene for this enzyme, known as isocitrate lyase, had concentrations of the disease-causing bacteria in their lungs similar to those in mice infected with normal M.
HCA is found helpful to block the fat formation process by inhibiting the citric lyase enzyme which is actually the responsible for fat formation process.