Because endometrial prostaglandin (PG) [F.sub.2[alpha]] production is critical for the induction of luteolysis , we hypothesize that LIF is involved in endometrial function for the production of luteolytic
Dupont et al., "Regulation of 3[beta]- hydroxysteroid dehydrogenase/[[DELTA].sup.5]-[[DELTA].sup.4] isomerase expression and activity in the hypophysectomized rat ovary: interactions between the stimulatory effect of human chorionic gonadotropin and the luteolytic
effect of prolactin," Endocrinology, vol.
agent promotes corpora lutea regression and subsequently induces parturition.
The injection of gonadorelin causes not only luteotrophic support but also prevents the luteolytic
mechanism by decreasing of plasma estradiol 17[beta] concentration and hence prohibits the rapid decreased of progesterone (Alaam et al., 1999).
Use of PG[F.sub.2[alpha]] immediately after parturition in cows induced earlier postpartum estrus suggested its strong luteolytic
effect and early resumption of ovarian activity.
is the natural luteolytic
agent that terminates the luteal phase of the oestrous cycle and allows for the initiation of a new one in the absence of fertilization, and it is particularly potent in terminating early pregnancy .
Effects of luteolytic
dose of oestradiol benzoate on uterine oxytocin receptor concentrations, phosphoinositide turnover and prostaglandin F-2a secretion in sheep.
Bah et al., "Is interleukin-1a a luteotrophic or luteolytic
agent in cattle?" Reproduction, vol.
In reproduction, PRL can have a luteotropic or luteolytic
action, depending on the stage of the reproductive cycle.
The lack of CL maintenance along with the estradiol valerate that is luteolytic
induces CL regression.