1989) and conceivably, lead to luteolysis
and embryonic loss.
Expression and localization of apelin and its receptor APJ in the bovine corpus luteum during the estrous cycle and prostaglandin F2alpha-induced luteolysis
Superoxide dismutase aetivity, lipid peroxide production and corpus luteum steroidogenesis during natural luteolysis
and regression induced by oestradiol deprivation of the ovary in pseudopregnant rabbits.
TNF-[alpha] has been shown to be potent stimulator of PGF2a synthesis in bovine endothelial cells which in turn in involved in luteolysis
(Blitek and Ziecik 2006) .
Furthermore, these observations indicate that regulation of Cx26 expression may be of critical importance in luteolysis
Various studies using protocols for synchronization based on progesterone and gonadotropin releasing hormone (GnRH) administration together with prostaglandin to induce luteolysis
during breeding season have yielded quite promising conception rates ranging from 30% to 50% (Table 1).
Probably, melatonin exerts its effect via a receptor-mediated action at the level of the ovary to modulate steroidogenesis (34), and possibly luteolysis
because it has been shown that melatonin [Mt.
As shown in Figure 1, the plasma progesterone concentrations on d-19 of the pregnant cows significantly decreased from those of luteal phase cows on d-19, suggesting the significant deviation occurred at the time of expected onset of luteolysis
The protocol effectively induced low LH levels and luteolysis
, but it only led to the collection of 3 oocytes in 49 oocyte retrievals resulting in 5 pregnancies (4 delivered).
During the luteolytic period, most pulses of OXT induce a pulse of PGF responsible for luteolysis
It has been reported that IL1B activates microsomal prostaglandin E2 synthase-1 (PTGES) in uterine tissues to stimulate synthesis of PGE2 for inhibition of luteolysis
in the porcine uterus (Franczak et al.
1988) wherein the concentration of estradiol 17p following luteolysis
increased and reached to its peak value either a day before or on the day of oestrous.