luteolysin

luteolysin

 [loo″te-ol´ĭ-sin]
a substance that causes degeneration of corpus luteum.

lu·te·ol·y·sin

(lū'tē-ol'i-sin),
Any natural or compounded agent which destroys the function of the corpus luteum.
[L. luteus, saffron-yellow, + G. lysis, dissolution]

luteolysin

An obsolete term for a substance that destroys or counteracts activity of the corpus luteum; the existence of luteolysins was questioned in 1970, and was later proved to be prostaglandin F2 alpha.

luteolysin

(loo″tē-ō-lī′sĭn) [L. luteus, yellow, + Gr. lysis, dissolution]
Something that promotes disintegration of the corpus luteum.
References in periodicals archive ?
Prostaglandin F2[alpha] is considered as principal luteolysin in domestic animals, which acts on the target cells via a specific plasma membrane-associate receptor (PTGFR [11]).
Although [PGF.sub.2[alpha]] seems to be a very potent luteolysin, its role in regulating the CL of pregnancy in cats is still uncertain.
It is clear that the uterus does not produce a luteolysin as in many nonprimate species.
During the peri-implantation period, the embryonic trophectoderm of the ruminant conceptus secretes the cytokine IFNT (Imakawa et al., 1987; Roberts et al., 1992), which acts on the uterine endometrium (Godkin et al., 1984) and attenuates endometrial production of the luteolysin prostaglandin F2[alpha], in turn maintaining corpus luteum function (Spencer et al., 1996; Salamonsen et al., 1998).