lupus profundus


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Related to lupus profundus: panniculitis, lupus tumidus

lu·pus er·y·the·ma·to·sus pro·fun·dus

a subcutaneous panniculitis with marked lymphocyte infiltration of fat lobules giving rise to deep-seated, firm, rubbery nodules that sometimes become ulcerated, usually of the face; may occur in systemic and localized lupus erythematosus.
Synonym(s): lupus profundus
Farlex Partner Medical Dictionary © Farlex 2012

lupus profundus

A deeply scarring, atrophic rash occasionally found in patients with systemic lupus erythematosus, caused by inflammation of subcutaneous fatty tissue.
Synonym: lupus panniculitis
See also: lupus
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
Lupus profundus is a chronic relapsing condition in which painful lesions may heal with significant lipoatrophy and scarring.
Lupus profundus is a rare presentation of LE and often presents as multiple subcutaneous nodules or plaques involving characteristic sites such as the upper arms, shoulders, buttocks, or face.
With respect to chronic cutaneous lupus, those with generalized discoid lesions have a 20% chance of developing SLE, those with lupus profundus are estimated to have a 10% chance, those with localized discoid lesions have a 5% chance, and those with lupus tumidus have virtually no chance.
Other LE specific features like papulosquamous rash starting initially as macules or papules on predominantly sun exposed areas occurred in 15 patients (50%), lupus profundus in one patient (3.34%) and Toxic epidermal necrolysis like lesions in one patient (3.34%).
The findings related to occurrence of LE specific features like malar rash, discoid rash and lupus profundus lesions, and LE nonspecific features like bullous lesions and Raynaud's phenomenon were found to be almost in consonance with those of Alakes Kumar Kole, et al study.