Effect of humidity on lung surfactant
films subjected to dynamic compression/expansion cycles.
. Biochim Biophys Acta 1974;344:241-61.
Comparison of Infasurf (calf lung surfactant
extract) to Survanta (beractant) in the treatment and prevention of RDS.
1 The Artificial Lung Surfactant
, Citracal, ET-2000 Guardrail End Treatment and Lycos, Inc.
The company anticipates a $40 million annual market for diagnosis of RDS and treatment with artificial lung surfactant
According to the company, it will display data from the effect of lung surfactant
on the in vitro activity of dalbavancin against Staphylococcus aureus and Streptococcus pneumoniae study and another dalbavancin-related study in San Diego Convention Center Halls F-H from 18 - 20 October 2012.
Other topics include secretion and absorption by colonic crypts, novel renal amino acid transporters, exocytosis of lung surfactant
, calcium-activated chloride channels, and the function of chloride channels in the kidney.
In this regard, it is important to keep in mind the role of lung surfactant
. Lung surfactant
is known to modulate immune functions in the lung (Wright 1997); we mention its role in particular because we have some preliminary data to suggest that lung surfactant
may enhance cytokine production in the lung fibroblasts.
(Nasdaq: DSCO), Doylestown, Pa., a biopharmaceutical company developing its proprietary surfactant technology as Surfactant Replacement Therapies for respiratory diseases, has initiated a Phase 1b clinical trial to evaluate the safety and tolerability of its humanized lung surfactant
, delivered as an inhaled aerosol, to treat hospitalized patients who suffer from asthma.
RESEARCH TRIANGLE PARK, N.C.--The Food and Drug Administration has approved a new protein-free synthetic lung surfactant
that is said to reduce the severity of respiratory distress syndrome, the most common cause of death and disability among premature infants.
Factors that have been postulated to contribute to altered permeability include lung hypoxia, chronicity of pulmonary collapse, rapid re-expansion and subsequent occurrence of strong negative pressure in the thorax, application of excessive intrathoracic suction pressure, rapid increase in blood flow to the involved lung during re-expansion, an increase in the pressure gradient between the alveolar space and the pulmonary capillary, disturbance of lymphatic flow in the 1ung, and destruction of lung surfactant