lung interstitium

lung interstitium

A general term for the connective tissue-rich supportive framework of the lung, which is divided into alveolar interstitium, axial interstitium, and peripheral interstitium.
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1) The histologic pulmonary findings show calcium deposition in the lung interstitium, alveolar septa and bronchial walls.
5) Pathologically, there is deposition of calcium salt in lung interstitium, the alveolar and vessel wall of normal lung.
DISCUSSION: Interstitial lung diseases are heterogeneous group of diseases involving lung interstitium.
In the case report, lung biopsies "demonstrated numerous spheroid silicone particles within the lung interstitium and small pulmonary vessels, surrounded by foreign body giant cells and nonnecrotizing granulomatous inflammation," 4 years after the patient reportedly "traveled to Mexico for silicone injections in the breasts and buttocks.
Patients present with lymphocytosis and diffuse lymphocytic infiltration limited to the lung interstitium.
The final stage is characterized by enhanced collagen deposition within the lung, expansion of the lung interstitium due to the proliferation of fibroblasts and smooth muscle cells, and increased expression of MMPs that participate in the remodeling of the injured tissue [20].
Flash pulmonary edema and acute pulmonary edema are terms used to define the sudden development of respiratory distress related to the rapid accumulation of fluid within the lung interstitium secondary to elevated cardiac filling pressures (Little, & Braunwald, 1997).
As left atrial pressure rises, pulmonary capillary pressures increase resulting in protein poor fluid (edema) being forced into the lung interstitium and alveoli.
Proteins entering the lung interstitium are constantly removed by lymphatic drainage.
The absence of tungsten in this case may be related to the character of the exposures associated with the specific process reported here; this process generates an unusually fine and highly heated aerosol characterized by particles that may be cleared more rapidly from the lung interstitium.
7) Proliferation and infiltration by LAM cells lead to the cystic destruction of the lung interstitium, obstruction of airways and pulmonary lymphatics, formation of cystic structures, and loss of pulmonary function.
Due to a confusing and often changing classification system, it is easy to become overwhelmed by the vast array of diseases that affect the lung interstitium, and developing a differential diagnosis based on isolated findings can be a challenging task.