lung interstitium

lung interstitium

A general term for the connective tissue-rich supportive framework of the lung, which is divided into alveolar interstitium, axial interstitium, and peripheral interstitium.
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In the case report, lung biopsies "demonstrated numerous spheroid silicone particles within the lung interstitium and small pulmonary vessels, surrounded by foreign body giant cells and nonnecrotizing granulomatous inflammation," 4 years after the patient reportedly "traveled to Mexico for silicone injections in the breasts and buttocks.
Patients present with lymphocytosis and diffuse lymphocytic infiltration limited to the lung interstitium.
The final stage is characterized by enhanced collagen deposition within the lung, expansion of the lung interstitium due to the proliferation of fibroblasts and smooth muscle cells, and increased expression of MMPs that participate in the remodeling of the injured tissue [20].
Due to a confusing and often changing classification system, it is easy to become overwhelmed by the vast array of diseases that affect the lung interstitium, and developing a differential diagnosis based on isolated findings can be a challenging task.
The first step to radiographic evaluation of interstitial lung disease begins with a fundamental working knowledge of the pertinent anatomy of the lung interstitium and the various patterns of its possible derangement.
Proteins entering the lung interstitium are constantly removed by lymphatic drainage.
7) Proliferation and infiltration by LAM cells lead to the cystic destruction of the lung interstitium, obstruction of airways and pulmonary lymphatics, formation of cystic structures, and loss of pulmonary function.