lower esophageal sphincter


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Related to lower esophageal sphincter: pyloric sphincter

low·er e·soph·a·ge·al sphinc·ter (LES),

musculature of the gastroesophageal junction that is tonically active except during swallowing.

lower esophageal sphincter

n.
A ring of smooth muscle fibers at the junction of the esophagus and stomach. Also called cardiac sphincter, gastroesophageal sphincter.

lower esophageal sphincter

A 3-5 cm in length zone of ↑ pressure at the junction of the distal esophagus with the gastric cardia, located at the hiatus, which forms a physical barrier in preventing gastric reflux; substances that ↑ the LES tone include gastrin, acetylcholine, serotonin, PGF2 a, motilin, substance P, histamine, pancreatic polypeptide

low·er e·soph·a·ge·al sphinc·ter

(LES) (lō'ěr es-ō-fa'jē-ăl sfingk'tĕr)
Musculature of the gastroesophageal junction that is tonically active except during swallowing.
References in periodicals archive ?
of subjects (n = 54) 0-5 0 5-10 13 10-15 21 15-20 15 20-25 5 Total 54 Mean BLESP 13.68 [+ or -] 3.93 [+ or -] SD BLESP, basal lower esophageal sphincter pressure.
Characteristics of lower esophageal sphincter function in symptomatic diffuse esophageal spasm.
This may be because, following the radiofrequency ablation to the deep submucosal space at the lower esophageal sphincter, collagen deposition needed time to mature.
Unfortunately, medications don't work for everyone, and a few patients may require a surgical procedure known as Nissen fundoplication, in which a surgeon wraps the upper part of the stomach (fundus) around the lower esophageal sphincter to strengthen it.
All trials included in the meta-analysis provided categorical information about the types of GERD-related symptoms (the incidence of TLESR, GER, gastric emptying, pharyngeal swallowing, and lower esophageal sphincter pressure and the acid reflux time).
This results in the lower end of the esophagus passing through a "tunnel" of stomach muscle, which strengthens the lower esophageal sphincter (LES), a ring of muscle tissue between the esophagus and the stomach.
GERD is a condition in which the lower esophageal sphincter, a muscular valve that separates the esophagus from the stomach, becomes too relaxed or weak and allows stomach acid to flow up into the esophagus, often causing considerable heartburn and other problems.
Unlike medical therapy, surgery was associated with normalization of lower esophageal sphincter pressure.
"Reflux is not caused by obstructive sleep apnea, but reflux may be facilitated by obstructive sleep apnea," she said, and called for more studies examining transient lower esophageal sphincter relaxations in obstructive sleep apnea patients.
Esophageal manometry revealed that the patient had an incompetent lower esophageal sphincter (LES), based on a resting pressure of only 3 mm Hg (figure 2); normal LES resting pressure ranges between 15 and 35 iron Hg (figure 3).
Because the lower esophageal sphincter is immature at birth, the esophagus is short, and the stomach is small, regurgitation is a normal fact of early life.
Melvin, "Radiofrequency energy delivery to the lower esophageal sphincter reduces esophageal acid exposure and improves GERD symptoms: a systematic review and meta-analysis.

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