low-molecular weight heparin

low-molecular weight heparin

Enoxaparin/Lovenox®, dalteparin, fraxiparin Pharmacology A heparin with advantages over unfractionated heparin, which blocks thrombosis earlier in the coagulation cascade than conventional heparin by inhibiting factor Xa; it less likely to cause thrombocytopenia or thrombotic thrombocytopenia syndrome Indications DVT. See Deep vein thrombosis.
References in periodicals archive ?
Comparison of low-molecular weight heparin and warfarin for the secondary prevention of venous thromboembolism in patients with cancer: a randomized controlled study.
Although low-molecular weight heparin (LMWH) and low dose aspirin (LDA) are generally considered safe, 10, 11 there is no direct evidence of their efficacy for miscarriage prevention.
Low-molecular weight heparin versus low-dose aspirin in women with one fetal loss and a constitutional thrombophilic disorder.
Reportedly, in preclinical studies, ISIS-FXIRx demonstrated potent antithrombotic activity with no increase in bleeding compared with standard anti-clotting agents, including low-molecular weight heparin, warfarin and Factor Xa inhibitors, all of which increased bleeding.
In their study, the researchers administered a fixed dose of plain heparin by syringe to half of the 708 volunteers and a low-molecular weight heparin, also by syringe, to the others.
Low-molecular weight heparin versus a coumarin for the prevention of recurrent venous thromboembolism in patients with cancer N Engl J Med 2003; 349:146-153.
Yet, Chinese market of heparin drugs, in particular the market of low-molecular weight heparin, is dominated by foreign brands on account of technology barriers although China is the worlds key supplier of heparin sodium API.
Low-molecular weight heparin versus aspirin and dipyridamole after femoropopliteal bypass grafting.
Using Premier's Perspective(TM) database, researchers from Premier compared actual inpatient treatments to evidence-based prophylaxis guidelines involving the use of unfractionated (UH) and low-molecular weight heparin (LMWH) and compression devices put forth by the American College of Chest Physicians for several categories of medical and surgical diagnoses.
The ENOX test is used to detect the anticoagulant effects of Aventis Pharmaceuticals' enoxaparin sodium (Lovenox(R)), the number-one selling low-molecular weight heparin (LMWH) in the world, in unstable angina patients.
The final payment represents the conclusion of a $5 million two year test development program as PharmaNetics and Aventis now initiate a collaborative marketing and promotion program to promote the use of the ENOX test to detect the anticoagulant effects of Aventis Pharmaceuticals' enoxaparin sodium (Lovenox(R)), the number-one selling low-molecular weight heparin (LMWH) in the world.
The first eight chapters describe the pharmacology and clinical utility of common antiplatelet, antithrombin, and fibrinolytic agents, including aspirin, the thieneopyridines, glycoprotein IIb/IIIa inhibitors, unfractionated heparin, the low-molecular weight heparins, and direct thrombin inhibitors.

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