low-grade lymphoma

low-grade lymphoma

Any relatively indolent lymphoma classified by the Working Formulation (a now-obsolete system for classifying lymphomas) as having a prolonged survival of 5 to 7.5 years, often with minimal therapy.
 
Examples
Small lymphocytic (plasmacytoid) lymphoma, follicular small cleaved cell lymphoma, follicular mixed small cleaved and large cell lymphoma.

low-grade lymphoma

Indolent lymphoma Any relatively indolent lymphoma classified by the Working Formulation, with a prolonged survival of 5 to 7.5 yrs, often with minimal therapy Examples Small lymphocytic–plasmacytoid lymphoma, follicular small cleaved cell lymphoma, follicular mixed small cleaved & large cell lymphoma. See Lymphoma, REAL classification, Working Formulation.
References in periodicals archive ?
Ten-year survival rate for low-grade lymphoma is 75%, and for the high-grade disease, 5-year survival rate is less than 50% (10).
(1-5) It is a low-grade lymphoma with an excellent prognosis.
Peter - partner at the practice in Thirsk, North Yorks, written about by James Herriot - said: "You fear the worst but it came back as a low-grade lymphoma, which wasn't too bad.
The new clinical trial is expected to involve 15 patients with low-grade lymphoma. Other experts have described the results as promising, but cautioned that what works on rodents in labs may not necessarily work on people.
In November 1997 she underwent bronchoscopy; washings showed "atypical lymphoid cells suspicious for lymphoma." The slides from the 1993 biopsy of the tissue around the right kidney were looked at again, and thought to be consistent with low-grade lymphoma, present but not recognized when her adenocarcinoma of the stomach was diagnosed.
While CTCL is often regarded as a low-grade lymphoma, it is slowly progressive and can take anywhere from several years to upwards of ten to reach tumor stage.
(iv) Nonlocalized bladder lymphoma occurred in 17 patients: one with low-grade lymphoma of the MALT type, four with follicle centre lymphomas, and 12 with large cell lymphomas.
Prognostic value of serum beta-2 microglobulin in low-grade lymphoma. Ann Intern Med.
Zelenetz et al., "Treatment of transformed and refractory low-grade lymphoma with Bexxar therapy is associated with improvements in quality of life," in Proceedings of the Annual Conference of the American Society of Hematology (ASH '01), 2001, abstract no 1790.
However, she has also been diagnosed with low-grade lymphoma. Although incurable it can be successfully kept at bay and next month she will start a two-year treatment programme involving a low dose of chemotherapy every eight weeks.
CTCL is a low-grade lymphoma and usually develops very slowly.

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