tolerance

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tolerance

 [tol´er-ans]
1. the ability to bear something potentially difficult.
2. the ability to endure unusually large doses of a poison or toxin.
3. drug tolerance. adj., adj tol´erant.
acquired drug tolerance drug tolerance.
ambiguity tolerance the ability to withstand conflicting or complex situations without undue psychological stress.
drug tolerance a decreasing response to repeated constant doses of a drug or the need for increasing doses to maintain a constant response. See also drug dependence and habituation.
immunologic tolerance specific nonreactivity of lymphoid tissues to a particular antigen capable under other conditions of inducing immunity.
standing tolerance the amount of time an individual is capable of maintaining an erect, upright position.
tolerance test
1. an exercise test to determine the efficiency of the circulation.
2. a test to determine the body's ability to metabolize a substance or to endure administration of a drug.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

tol·er·ance

(tol'ĕr-ăns),
1. The ability to endure or be less responsive to a stimulus, especially over a period of continued exposure.
2. The power of resisting the action of a poison or of taking a drug continuously or in large doses without injurious effects.
[L. tolero, pp. -atus, to endure]
Farlex Partner Medical Dictionary © Farlex 2012

tolerance

(tŏl′ər-əns)
n.
1.
a. Physiological resistance to a toxin.
b. Diminution in the physiological response to a drug that occurs after continued use, necessitating larger doses to produce a given response.
c. The ability to digest or metabolize a food, drug, or other substance or compound: glucose tolerance.
2.
a. Acceptance of a tissue graft or transplant without immunological rejection.
b. Unresponsiveness to an antigen that normally produces an immunologic reaction.
3. The ability of an organism to resist or survive infection by a parasitic or pathogenic organism.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

tolerance

Immunology Immune unresponsiveness to an antigenic challenge. See Immune tolerance, Self-tolerance Pharmacology An ↑ in dose of a drug required to achieve the same effect in a particular Pt, which is a function of ↑ metabolism–eg, by hypertrophy of the endoplasmic reticulum or ↑ expulsion of the drug from a cell–eg, amplification of the multidrug resistant gene by malignant cells. See Oral tolerance, MDR Psychiatry Resistance to the effects of a sedative Substance abuse
1. A state caused by regular use of opioids, where an increased dose is needed to produce the desired effect; tolerance may be a predictable sequelae of opioid use and does not imply addiction. See Drug tolerance, Physical dependence.
2. The ability to 'hold liquor'–consume alcohol without overt signs of inebriation Vox populi A general term for a person's general 'mellowness,' which encompasses the ability to cope with stress, acceptance of others, complete with bumps and flaws, and other facets of social intelligence.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

tol·er·ance

(tol'ĕr-ăns)
1. The ability to endure or be less responsive to a stimulus, especially over a period of continued exposure.
2. The power of resisting the action of a poison or of taking a drug continuously or in large doses without injurious effects.
[L. tolero, pp. -atus, to endure]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

tolerance

  1. the ability of an organism to withstand harsh environmental pressures such as drought or extreme temperatures.
  2. the ability of an organism to withstand the build up of an adverse factor such as pesticides or endoparasites within itself without showing serious symptoms of attack.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005

Tolerance

A phenomenon whereby a drug user becomes physically accustomed to a particular dose of a substance, and requires increasing dosages in order to obtain the same effects.
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.

tol·er·ance

(tol'ĕr-ăns)
1. Ability to endure or be less responsive to a stimulus, especially over a period of continued exposure.
2. Power of resisting the action of a poison or of taking a drug continuously or in large doses without harm.
[L. tolero, pp. -atus, to endure]
Medical Dictionary for the Dental Professions © Farlex 2012

Patient discussion about tolerance

Q. When will I have the Glucose Tolerance Test? I am pregnant and wanted to know when I need to have the Glucose Tolerance Test and what is the test like.

A. The test is given between week 24 and week 28 of the pregnancy. First you drink glucose, which is very sweet. You can mix it will water to help it go down easier. Then, after an hour you will have a blood test to check your glucose levels.

Q. What Do my Oral Glucose Tolerance Test Results Mean? I had an Oral Glucose Tolerance Test last week. I am 26 weeks pregnant. The results I got are 132 mg/dL. What does this mean?

A. If your blood glucose level was greater than 130 mg/dL, your provider will likely recommend you take another diabetes screening test that requires you to fast (not eat anything) before the test. During this second test, called the 100-gram oral glucose tolerance test, your blood glucose level will be tested four times during a three-hour period after drinking the cola-like drink. If two out of the four blood tests are abnormal, you are considered to have gestational diabetes.

Q. I want to know the types of therapy to treat Bipolar Disorder. My aunty is suffering from Bipolar disorder. I couldn’t tolerate her suffering. So I want to know the types of therapy to treat this?

More discussions about tolerance
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