low osmolar contrast agent

low osmolar contrast agent (LOCA),

nonionic water-soluble radiographic contrast material.

low os·mo·lar con·trast a·gent

(lō oz-mō'lăr kon'trast ā'jĕnt)
Nonionic water-soluble radiographic contrast material.
Synonym(s): low osmolar contrast medium, nonionic contrast agent.
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In it, patients with high-risk cardiac conditions, such as evolving acute MI, unstable angina, or post-MI ischemia, were randomly assigned to receive either the nonionic isosmolar contrast agent Visipaque(R) (iodixanol), or the ionic low osmolar contrast agent ioxaglate, during their coronary artery balloon angioplasty and/or stent placement procedures.

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