loosen(redirected from loosening up)
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v. loos·ened, loos·ening, loos·ens
1. To make looser or less tight: loosened his tie; loosened her grip on the rope.
2. To free (the bowels) from constipation.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.