loop diuretics

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Related to loop diuretics: potassium sparing diuretics

loop diuretics

Drugs that lead to a large output of water in the urine by interfering with the reabsorption of sodium and chloride in the loop of Henle tubules in the kidneys. They include FRUSEMIDE (furosemide) (Fru-Co, Frumil, Frusene, Frusol, Lasikal, Lasilactone, Lasix); BUMETANIDE (Burinex, Burinex A, Burinex K); and torasemide (Torem). Frusemide is commonly formulated in combination with the thiazide diuretic AMILORIDE.

diuretics

powerful drugs, often termed 'water tablets', that control hypertension and peripheral oedema; action of some local anaesthetics is antagonized by concomitant use of some diuretics (see Table 1), e.g. aldosterone antagonists (e.g. spironolactone); carbonic anhydrase inhibitors, e.g. acetazolamide; loop diuretics, e.g. furosemide; osmotic diuretics, e.g. mannitol; potassium-sparing diuretics, e.g. amiloride, or in combination with other diuretics; thiazide diuretics, e.g. bendroflumethiazide

**Table 1:** Principal drug interactions of local anaesthetic agents and other medications
Local anaesthetic agent Proprietary name	Principal drug interactions	Effect of interaction
Lidocaine Xylocaine	Antiarrhythmic agents Antibacterial agents Antipsychotics Antivirals Beta-blockers Diuretics Dolasetron Ulcer-healing drugs	Increased myocardial depression Increased risk of ventricular arrhythmias if lidocaine is given with quinpristin/dalfopristin Increased risk of ventricular arrhythmias if lidocaine is given with any drug that prolongs the QT interval of the cardiac cycle Plasma concentration of lidocaine increased by amprenavir, atazanavir and lopinavir Increased myocardial depression Increased risk of lidocaine toxicity when given with propranolol The action of lidocaine is antagonized by the hypokalaemia caused by acetazolamide, loop diuretics or thiazide and related diuretics (i.e. a greater dose of lidocaine would be required to achieve anaesthesia) Increased risk of ventricular arrhythmia if lidocaine is given with dolasetron Plasma concentration of lidocaine increased when given with cimetidine; risk of lidocaine toxicity increased with cimetidine
Bupivacaine Marcain Levo-bupivacaine Chirocaine	Beta-blockers	Increased risk of bupivacaine toxicity when given with propranolol Increased risk of myocardial depression if given with other antiarrhythmic agents
Prilocaine Citanest	Antiarrhythmic agents Antibacterial agents	Increased risk of myocardial depression if given with antiarrhythmic agents Increased risk of methaemoglobinaemia if given with sulphonamide antibacterial agents
Ropivacaine Naropin	Antidepressants	Metabolism of ropivacaine is inhibited by fluvoxamine, thereby enhancing the risk of ropivacaine toxicity
Mepivacaine Scandonest	Drug not listed in the British National Formulary

References in periodicals archive ?

Loop diuretics have been shown to accelerate NOF in hypertensive patients who use them continuously for more than three years.

Long-term Effects of Antihypertensive Drug Use and New-onset Osteoporotic Fracture in Elderly Patients: A Population-based Longitudinal Cohort Study

Beyond aggressive treatment with loop diuretics, what else is useful in achieving the goal of hospital discharge with normalized filling pressures?

Acute heart failure: What works, what doesn't

The key to next differentiate these 2 possibilities is measuring urine calcium excretion, which is high in BS (owing to a mutation in 1 of 5 different genes in the TAL, the region of the kidney impacted by loop diuretics and important for calcium reabsorption), but low in GS (owing to a mutation in NCCT).

A rare case of hypokalemia and hypomagnesemia

Thiazide and loop diuretic are no doubt very effective anti-hypertensive drugs and they are also economically priced but they are not for every patient suffering from high blood pressure.

Interview: Prof. Austin Stack from Ireland - Management of Hyperuricemia and Gout: Gout patients can continue taking Low Dose Aspirin therapy to get protection from cardiac diseases

Once the diagnosis made immediate treatment by loop diuretics, sodium replacement.

Gynaecological TURP syndrome

Furosemide from Lasix, Sanofi-Aventis Farmaceutica, a highceiling loop diuretic, was used as reference drug (positive control).

Diuretic and antilithiasic activities of ethanolic extract from Piper amalago (Piperaceae)

angiotensin-converting enzyme inhibitors, cyclosporine, diuretics: loop diuretics and thiazides; non-steroidal anti-inflammatory drugs, tetracycline), overdose, renal insufficiency, schizophrenia, surgery and volume depletion are among the factors that increase the risk for toxicity in previously stable patients (4).

Our good, (g)old lithium

MEDICATIONS THAT MAY AFFECT CALCIUM ABSORPTION Loop diuretics Furosemide (Lasix), bumetanide (Bumex), torsemide (Demadex) Cortico steroids Cortisone, prednisone, prednisolone (Prelone), methylprednisolone (Medrol) Heartburn medications Esomeprazole magnesium (Nexium), omeprazole (Prilosec), lansoprazole (Prevacid), cimetidine (Tagamet), ranitidine hydrochloride (Zantac) Laxatives Ex-Lax, Correctol

Some medications and conditions may inhibit calcium absorption: Protect your bones by knowing if you're taking a calcium-blocking drug, and adjust your medication schedule and calcium intake accordingly

The presently available diuretics such as thiazides and loop diuretics exhibit various adverse effects, such as electrolyte imbalance and metabolic alterations.

Potential interaction of green tea extract with hydrochlorothiazide on diuretic activity in rats

It is well accepted that the therapeutic approach of decompensated CHF includes the use of intravenous loop diuretics to decrease sodium and water retention.

Predisposing factors for acute kidney injury in hispanic patients treated with diuretics for decompensated heart failure

Loop diuretics are commonly prescribed to heart failure patients because they help reduce fluid buildup in the body, a common problem facing these individuals.

Least-prescribed loop diuretic may be most helpful for heart failure patients: research shows that torsemide's effects may last longer and be better tolerated, but the drug is pricier and some doctors say a weaker diuretic is adequate for many people

In the study, RLX030 was given on admission to the hospital in the form of an intravenous infusion for up to 48 hours in addition to loop diuretics and other medicines and was compared to placebo on top of standard of care treatment for AHF.

Switzerland : Results from Novartis Phase III study show that RLX030 reduced deaths in patients with acute heart failure