microRNA hairpin

(redirected from long double-stranded RNA)

microRNA hairpin

A long RNA molecular that is processed by the enzyme Dicer to form siRNAs or miRNAs, which are used by an RNAi-silencing complex to either degrade mRNA (RNAi) or to translationally repress the mRNA (siRNA) inhibitor in vivo.
References in periodicals archive ?
In this way, detection of the RNA cancer marker triggers the self-assembly of a long double-stranded RNA polymer.
If PKR indeed detects long double-stranded RNA within a cell, the protein triggers a cell-death pathway to eliminate the cell.
RNA interference involves introducing long double-stranded RNA into an organism, which degrades the targeted homologous mRNA.