lomefloxacin


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antibiotic

 [an″te-, an″ti-bi-ot´ik]
1. destructive of life.
2. a chemical substance produced by a microorganism that has the capacity, in dilute solutions, to kill other microorganisms or inhibit their growth. Antibiotics that are sufficiently nontoxic to the host are used as chemotherapeutic agents in the treatment of infectious diseases. See also antimicrobial agent.
antineoplastic a's (antitumor a's) a class of antineoplastic agents that apparently affect the function or the synthesis, or both, of nucleic acids and thus are cell cycle nonspecific. See also antineoplastic therapy.
broad-spectrum antibiotic one that is effective against a wide range of bacteria, both gram-positive and gram-negative.
β-lactam antibiotic any of a group of antibiotics, including the cephalosporins and the penicillins, whose chemical structure contains a β-lactam ring.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

lomefloxacin

Maxaquin® Infectious disease A broad-spectrum quinolone for treating uncomplicated and complicated UTIs, prophylaxis of bacterial infection in posttransurethral surgery and transrectal prostate biopsy, for acute bacterial exacerbation of chronic bronchitis gram-negative bacilli, staphylococci. See Fluoroquinolone.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Ten (fluoro)quinolones were detected in the samples (orbifloxadn, danofloxacin, pipemidic acid, marbofloxacin, lomefloxacin, pefloxacin, enrofloxacin, norfloxacin, ciprofloxacin, and ofloxacin) with concentrations ranging from below the limit of detection (LOD) to 244 ng/mL in wastewater samples and 20.4 ng/g in soil samples [see Supplemental Material, Table S5 (http://dx.doi.org/10.1289/ehp.1104776)].
Antibiotics were diluted in agar at concentrations from 0.002 to 16.0 [micro]g/ml for ciprofloxacin, 0.0078 to 16.0 [micro]g/ml for ofloxacin and 0.0078 to 16.0 [micro]g/ml for lomefloxacin. Reference strains (WHO A-E) with known MICs were co-tested with samples as control.
Proposed criteria for interpretation of susceptibilities of strains of Neisseria gonorrhoeae to ciprofloxacin, ofloxacin, enoxacin, lomefloxacin, and norfloxacin.
Cost of Oral Quinolone Therapy Cost(*) per Cost(*) per Quinolone Regimen Dose, $ 7 Days, $ Ciprofloxacin 250 mg bid 2.70 37.80 500 mg bid 3.13 43.82 750 mg bid 5.43 76.02 Enoxacin 200 mg bid 2.73([dagger]) 38.22 Lomefloxacin 400 mg daily 6.11 42.77 Norfloxacin 400 mg bid 2.54 35.56 Ofloxacin 200 mg bid 3.06 42.84 300 mg bid 3.64 50.96 400 mg bid 3.84 53.76 (*) Average wholesale price, 1995.
Kedor-Hackmam, "Quantitative determination of gatifloxacin, levofloxacin, lomefloxacin and pefloxacin fluoroquinolonic antibiotics in pharmaceutical preparations by high-performance liquid chromatography," Journal of Pharmaceutical and Biomedical Analysis, vol.
Antibiotics resistant to Staphylococcus aureus were Gentamicin, Amikacin, Cotrimoxazole, Lomefloxacin. Out of a total of 27 (i.e.
Quinolones (ciprofloxacin, levofloxacin, ofloxacin, norfloxacin, pefloxacin, enoxacin, fleroxacin, lomefloxacin, and other new ones) have a favorable pharmacokinetic profile, with excellent oral bioavailability (greater than 95%) for most.
Following the procedure, the patient was treated with topical lotoprednol (Lotemax[R], Bausch+Lomb, USA) drops four times daily and topical lomefloxacin (Okacin[R], Novartis, Switzerland) drops four times daily.
Wang, A novel spectrofluorimetric method for determination of lomefloxacin based on supramolecular inclusion complex between it and p-sulfonated calyx[4]arene, Anal.
Mashima, "Aqueous humor levels of topically applied levofloxacin, norfloxacin, and lomefloxacin in the same human eyes," Journal of Cataract and Refractive Surgery, vol.
In studies based on isolates from treated patients, GAT along with moxifloxacin was found to be most effective followed by SPX, OFL, CIP and lomefloxacin (11,12,21,34-37).
The newer ones--such as lomefloxacin, sparfloxacin, and trovafloxacin--are better against anaerobes than the older ones.