), which has a MW of about 296, is used to mitigate opioid withdrawal symptoms to facilitate abrupt opioid discontinuation in adults.
The Federal Drug Administration recently approved lofexidine
, the first medication for use in reducing symptoms associated with opioid withdrawal in adults.
introduction of Lucemyra (lofexidine
) 0.18 mg tablets, the first and only non-opioid medication indicated for mitigation of opioid withdrawal symptoms to facilitate abrupt opioid discontinuation in adults.
Therapy company Camargo Pharmaceutical Services LLC announced on Monday the US Food and Drug Administration's approval through its 505(b)(2) pathway for LUCEMYRA (lofexidine
) tablets for mitigation of opioid withdrawal symptoms to facilitate abrupt opioid discontinuation in adults.
THURSDAY, May 17, 2018 (HealthDay News) -- Lucemyra (lofexidine
hydrochloride) has been approved by the U.S.
Adrenergic drugs such as Clonidine and Lofexidine
have been found to help decrease excessive cravings and use of opiates.
Major disruptions of sleep during treatment of the opiate withdrawal syndrome: differences between methadone and lofexidine
He was treated with sodium valproate (1.2g/d), risperidone (4mg/d) and lofexidine
Wang et al., "A double-blind clinical trial of Jitai tablets vs Lofexidine
in the treatment of heroin withdrawal symptoms," Chinese Journal of Drug Dependence, vol.
Effects of THC and lofexidine
in a human laboratory model of marijuana withdrawal and relapse.
Buprenorphine's effectiveness for opiate detoxification compared to clonidine, lofexidine
, and methadone have been the subject of a Cochrane review.