CT scans similarly give a cobweb appearance of
loculated fluid with septations within, containing material with the attenuation properties of fluid or hemorrhage.
The company's lead drug, LTI-01, is in development for
Loculated Pleural Effusion and has successfully completed a clinical trial in LPE patients.
Ultrasonographic appendix diameter (>7mm), presence of thickened wall, and surrounding
loculated fluid collection were evaluated.
It also revealed a 3.1 x 1.9 cm dumbbell-shaped
loculated fluid collection anterior to the anus consistent with perirectal abscess (Figure 3) confirming the etiology of his rectal discomfort.
Compared with computed tomography (CT), ultrasound is more sensitive in distinguishing the pleural fluid from pleural thickening and pleural masses and in the detection of thin septations in
loculated effusions [2, 3, 6, 7].
While in MICU, transthoracic echocardiogram was done, which revealed normal left ventricular (LV) systolic function (ejection fraction > 55%) and severe tricuspid regurgitation (coronary sinus and right atrium were noted to be dilated, and a small
loculated pericardial effusion was seen behind the right atrium, with no evidence of cardiac tamponade.
While, in the ED, urology was consulted and requested interventional radiology to drain the urinoma and to place a Foley catheter to monitor urine output, the attending physician, at the request of interventional radiology, performed a needle aspiration of the
loculated fluid collection in the right flank via ultrasound and noted a small amount of purulent and urine-like fluid from two separate areas of collection.
A
loculated component along the left upper lung insinuated through the chest wall into the left pectoralis muscle, raising the possibility of empyema necessitans (Figures 1 and 2).
Caption: Figure 2: Contrast-enhanced CT thorax: large
loculated rightsided pleural effusion.
Chest X-ray (CXR) (PA and lateral views) in the emergency department revealed a cavitary lesion with an air-fluid level within the anterior medial right hemithorax and a
loculated hydropneumothorax along the right lateral lung base (Figure 1).
The chest CT revealed a partly
loculated, large left pleural effusion with complete atelectasis of the left lower lobe and partial atelectasis of the left upper lobe.
Ultrasound guidance may be required in case of
loculated effusion.