Unfortunately, only 10% of pancreatic cancer patients have
localized disease, leaving a large unmet medical need for treatment in 90% of the pancreatic cancer patient population.
In the United States of America (USA), the five year survival is 99% for
localized disease, 85% for regional and 27 % for distant disease .
burgdorferi may experience symptoms associated with three stages: early
localized disease, early disseminated disease, and late persistent disease1.
The most characteristic symptom of early
localized disease is the appearance of erythema migrans on the skin.
From the above study, it was concluded that prognosis for
localized disease was very good and most cases recovered uneventfully.
The study involved 1,148 men with clinically
localized disease who were treated with surgery (63 percent) or radiotherapy (37 percent).
b) Insufficient treatment (undertreatment) and relapse in patients initially considered low-risk patients with favorable prognosis and
localized disease;
Disease extent (metastatic versus
localized disease) is an important risk factor [17], as well as primary tumor site and size in case of
localized disease.
(1) One review of 40 breast amyloidosis cases reported that 53 percent of patients presented with
localized disease restricted to the breast while the remaining 47 percent had systemic illness.
For
localized disease, surgery with wide local excision plus adjuvant radiation therapy can be used.
In patients with
localized disease, a wide excision generally minimizes the chance of local recurrence.
(9) Despite the poor results associated with systemic JXG, the vast majority of JXG patients have
localized disease, which is associated with an excellent prognosis.