noninfiltrating lobular carcinoma

(redirected from lobular neoplasia)

non·in·fil·trat·ing lob·u·lar car·ci·no·ma

carcinoma of the breast in which small tumor cells fill preexisting acini within lobules, without invading the surrounding stroma.
References in periodicals archive ?
The term lobular neoplasia has been applied to the spectrum of lesions comprising atypical lobular hyperplasia (ALH) and LCIS.
Their topics include nonproliferative alterations of acini, lobular neoplasia and its distinction form other epithelial proliferative lesions, invasive carcinoma: special types and important considerations, benign and reactive stromal lesions, vascular lesions, and male breast.
INTRODUCTION: Insitu breast carcinomas are classified, according to their morphology, as ductal carcinoma insitu (DCIS) or lobular neoplasia (LN), which includes lobular carcinoma insitu (LCIS) and atypical lobular hyperplasia (ALH).
The role of MRI for surveillance of patients with lobular neoplasia in association with additional risk factors continues to be evaluated (Venkitaraman, 2010).
PASH like changes is also incidentally detected with other breast lesions such as fibrocystic disease, fibroadenomas, columnar cell lesions, lobular neoplasia and in situ and invasive ductal carcinoma.
BOSTON -- Ductal lavage is technically feasible in patients diagnosed with lobular neoplasia, reported Marie Ward, M.
The remaining 82% (146 of 177) of MRI-guided biopsies were nonmalignant, of which 71% (126 of 177) revealed benign changes (or no pathologic findings) and 11% (20 of 177) showed epithelial atypia, which includes 17 cases of lobular neoplasia and 3 cases of atypical ductal hyperplasia.
DIFFERENTIAL DIAGNOSIS OF LOBULAR NEOPLASIA VERSUS DUCTAL NEOPLASIA
Estimates from more recent series of core biopsies suggest that at least 1% to 2% of all breast core biopsies contain ADH or lobular neoplasia (ALH and lobular carcinoma in situ).
The term lobular neoplasia (LN) was introduced by Haagensen et al (1) in 1978 and encompasses the spectrum of disease including atypical lobular hyperplasia (ALH) and lobular carcinoma in situ (LCIS), the latter of which is further divided into classic and pleomorphic types.
14-17) Furthermore, the inherent subjectivity in rendering a morphologic diagnosis of LCIS can represent an additional variable, and many studies have used the term lobular neoplasia to encompass LCIS and ALH lesions.
2,6) Lobular neoplasia or lobular carcinoma in situ can involve papillary lesions.