noninfiltrating lobular carcinoma

(redirected from lobular neoplasia)

non·in·fil·trat·ing lob·u·lar car·ci·no·ma

carcinoma of the breast in which small tumor cells fill preexisting acini within lobules, without invading the surrounding stroma.
References in periodicals archive ?
The management of atypical lobular hyperplasia (ALH) and lobular carcinoma in situ (LCIS), together known as lobular neoplasia (LN), as the most significant lesion on core biopsy remains controversial in spite of a relatively large number of publications dealing with the topic.
Proliferative lesions with atypia include fat atypia, atypical ductal hyperplasia (ADH) and lobular neoplasia (atypical lobular hyperplasia (ALH), lobular carcinoma in situ) (12).
(7) In a small study from MD Anderson Cancer Center, women with lobular neoplasia (ALH, lobular carcinoma in situ; LCIS) by core biopsy underwent an excision and 40% were found to have a more significant lesion.
Their topics include nonproliferative alterations of acini, lobular neoplasia and its distinction form other epithelial proliferative lesions, invasive carcinoma: special types and important considerations, benign and reactive stromal lesions, vascular lesions, and male breast.
INTRODUCTION: Insitu breast carcinomas are classified, according to their morphology, as ductal carcinoma insitu (DCIS) or lobular neoplasia (LN), which includes lobular carcinoma insitu (LCIS) and atypical lobular hyperplasia (ALH).
The role of MRI for surveillance of patients with lobular neoplasia in association with additional risk factors continues to be evaluated (Venkitaraman, 2010).
PASH like changes is also incidentally detected with other breast lesions such as fibrocystic disease, fibroadenomas, columnar cell lesions, lobular neoplasia and in situ and invasive ductal carcinoma.
BOSTON -- Ductal lavage is technically feasible in patients diagnosed with lobular neoplasia, reported Marie Ward, M.D.
Carcinomas of lobular epithelial origin are usually divided on the basis of invasion, that is, lobular cancer in situ (or lobular neoplasia) and invasive lobular cancer.
When present, lobular neoplasia, encompassing ALH and lobular carcinoma in situ (LCIS), is often multifocal and bilateral.
The term lobular neoplasia has been applied to the spectrum of lesions comprising atypical lobular hyperplasia (ALH) and LCIS.
The remaining 82% (146 of 177) of MRI-guided biopsies were nonmalignant, of which 71% (126 of 177) revealed benign changes (or no pathologic findings) and 11% (20 of 177) showed epithelial atypia, which includes 17 cases of lobular neoplasia and 3 cases of atypical ductal hyperplasia.