Pleomorphic
lobular carcinoma in situ (PLCIS) on breast core needle biopsies: clinical significance and immunoprofile.
Characteristics of Ductal Carcinoma In Situ and
Lobular Carcinoma In Situ Classification of Lesion Ductal Carcinoma in situ Diagnosis Clinical presentation Palpable lesion often present (Bland, 2011; Choi et al.
However, on rare occasions, there may be sampling error, which occurred in one case in our study where a subsequent ultrasound guided biopsy of the area revealed focal
lobular carcinoma in situ in a background of columnar cell lesion.
The subset analysis of the P-1 trial that was reported at the meeting included 826 women with a history of
lobular carcinoma in situ (LCIS) and 1,193 women with a history of atypical hyperplasia (AH); both high-risk conditions were diagnosed by breast biopsy.
The ''Rosen Triad'': tubular carcinoma,
lobular carcinoma in situ, and columnar cell lesions.
Simultaneous loss of E-cadherin and catenins in invasive lobular breast cancer and
lobular carcinoma in situ.
Recently recognized variants of
lobular carcinoma in situ (LCIS) with an emphasis on management of LCIS on core needle biopsy.
A, Low-power view resembles a solid pattern of ductal carcinoma in situ or
lobular carcinoma in situ.
A, Classical invasive lobular carcinoma and
lobular carcinoma in situ of the breast are characterized by loosely cohesive cells displaying low cytologic atypia, absence of significant pleomorphism, and scant cytoplasm.
Occult neoplastic epithelial proliferations identified in 4 nipples (Table 1) included primary disease with 1 case of
lobular carcinoma in situ involving TDLU in the nipple (Figure 2, A) and 1 case of Paget disease with lesion measuring 0.
Lobular carcinoma in situ (LCIS) and atypical lobular hyperplasia (ALH) are infrequent findings in needle core biopsy samples, occurring in approximately 0.
Finally, comedo-type DCIS lesions often need to be distinguished from the pleomorphic subtype of
lobular carcinoma in situ (LCIS) lesions.
