liver function test


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liver function test (LFT)

one of several tests used to evaluate various functions of the liver, including metabolism, storage, filtration, and excretion. Kinds of liver function tests include alanine aminotransferase test, alkaline phosphatase test, prothrombin time, serum bilirubin.

liver function test

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LFT

A blood test for a specific aspect of liver metabolism. Because of the diversity of liver functions and the disorders that may affect those functions, no single test provides a reliable measure of overall liver function. The ability to excrete bile pigments is measured by determining the serum bilirubin level; the levels of serum enzymes such as the aminotransferases aspartate and alanine may be used to assess damage to the liver cells and biliary tract obstruction or dysfunction. Levels of the serum proteins albumin and globulin and their ratio are used to judge the synthetic functions of the liver. Certain blood clotting factors are also synthesized in the liver, and abnormalities may indicate impairments in hepatic synthesis. Blood ammonia levels are elevated in some patients with either acute or chronic liver disease; marked elevations may suggest acute or chronic liver failure.
See: liver
References in periodicals archive ?
Presenting symptoms include abdominal pain, fever, hepatomegaly, and abnormal liver function tests with elevation of LDH higher than that of ALT.
Fasting serum levels of liver function tests, including ALT, AST, alkaline phosphatase (ALP), albumin, and total and direct bilirubin, were measured 4 times: before, during (the second and last weeks), and a month after the holy month of Ramadan.
Study of liver function tests and real function tests and real function tests in diabetic Type-II patients" J.
Excessive monitoring can lead to premature discontinuation of therapy because 10%-20% of patients develop some liver function test elevation.
01 Table 2: Liver function test indices before and after surgery (mean [+ or -] SD) Indices Before surgery After surgery P value Direct bilirubin 0.
We conclude that the routine inclusion of total protein in liver function test profiles is useful for the detection of new patients with paraproteins.
The first- or second-generation positive EIA should be followed by a supplementary test, such as the RIBA-2 assay or liver function test.
In the study of comparison of mean activity of various parameters in different types of non-liver diseases it is found that serum cholinesterase levels were within normal range in each group of patients while other parameters of conventional liver function test were fluctuating in different group of patients.
We describe a patient in whom cholestatic-llkc disturbances of liver function tests were detected shortly after initiating therapy with enalapril.
The trial will also enroll patients with PAH receiving prostacyclin or sildenafil therapy at baseline, and patients who previously discontinued either bosentan, sitaxsentan, or both, due to liver function test abnormalities.