From January 15 through December 27, 2016, a total of 1,297 pregnancies with possible recent Zika virus infection were reported to the USZPR from 44 states (Figure 1), including 972 completed pregnancies with reported outcomes (895 liveborn infants
and 77 pregnancy losses).
Applied to a population with maternal ages similar to the entire US population delivering liveborn infants
, the Down syndrome detection rate and false-positive rate for laboratory 1 were expected to be 82.8% and 7.8%, respectively.
And, among those women in the study group who deliver liveborn infants
, they will randomly assign postpartum education that includes either general information about infant care or the promotion of exclusive breastfeeding.
We recently completed a retrospective study to correlate placental lesions with clinical neurologic findings in liveborn infants
with intrauterine growth restriction (IUGR).
In 2000, a total of 529 congenital syphilis cases were reported, for a rate of 13.4 per 100,000 liveborn infants
. That's a 7.6% decline from 1999 and a 51.8% drop since 1997.
Among liveborn infants
, 59% had Zika laboratory testing results reported to the pregnancy and infant registries.
The researchers reported on a case series of 1,501 liveborn infants
with suspected congenital Zika virus syndrome reported in Brazil.
They noted that congenital microcephaly is rare in the United States (only about 6 cases in 10,000 liveborn infants
) but that the number of cases in Brazil and French Polynesia is much in excess of what would be predicted in the absence of the ZV epidemic.
DS is the most common chromosomal disorder in liveborn infants
, with no predilection for race or socioeconomic group.
The passage of foetal colonic contents in the amniotic cavity causes the MSAF and is a commonly encountered finding in the obstetric practice with an overall frequency between 12% and 19%.8,9 It is more common in post-term pregnancies and with intrauterine growth restriction.10 The MSAF is associated with a lot of adverse outcomes and has long been considered to be a bad predictor of foetal outcome.11,12 The MAS is the most common cause of respiratory disease in terms of infants13 and has been reported in 6.6% to 30% of cases of MSAF, and 1% to 3% of liveborn infants
.14 The MSAF causes low apgar score at birth, foetal academia and hypoxia.
Abruptio placentae is a serious condition with a high mortality rate; liveborn infants
frequently have neonatal complications, including birth asphyxia and the hazards of prematurity, what rises the need for medical intervention.
A prospective cohort study was done among 681 HIV positive pregnant women in the Latin American and Caribbean region receiving one of three different antiretroviral regimens for at least 28 days during pregnancy and who delivered liveborn infants
with known birthweight and gestational age in 2005.