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Related to liquid-based cytology: smear test, Cervical cytology
liquid-based cytologyAbbreviation: LBC
A means of performing a Papanicolaou test (Pap test) in which the head of the plastic spatula used to obtain cells from the endocervix is inserted directly into a vial containing a fluid cellular preservative. The vial is spun in the laboratory, and a pellet of pure cells is obtained. This cellular layer is then deposited on a microscope slide and examined for evidence of cellular atypia or frank cancer. The liquid-based cytology differs from traditional cervical cytology in that the contents of the spatula are not smeared directly onto a microscope slide. This reduces the number of specimens received by the laboratory that are unable to be interpreted pathologically.
See also: cytology