liquid-based cytology


Also found in: Dictionary, Thesaurus, Encyclopedia.
Related to liquid-based cytology: smear test, Cervical cytology

liquid-based cytology

Abbreviation: LBC
A means of performing a Papanicolaou test (Pap test) in which the head of the plastic spatula used to obtain cells from the endocervix is inserted directly into a vial containing a fluid cellular preservative. The vial is spun in the laboratory, and a pellet of pure cells is obtained. This cellular layer is then deposited on a microscope slide and examined for evidence of cellular atypia or frank cancer. The liquid-based cytology differs from traditional cervical cytology in that the contents of the spatula are not smeared directly onto a microscope slide. This reduces the number of specimens received by the laboratory that are unable to be interpreted pathologically.
See also: cytology
References in periodicals archive ?
The present study was undertaken to prepare liquid-based smears and cell blocks from Liquid-based cytology specimens to aid in the diagnosis of Pap smears and to correlate with histopathology wherever possible.
Specimen adequacy of liquid-based cytology and cell block
Liquid-based cytology in the fine needle aspiration of parathyroid lesions: a comparison study with the conventional smear, ThinPrep, and SurePath.
An analysis of the results of colposcopy, which was performed in 2,609 women found to have atypical squamous cells of undetermined significance (ASCUS) or worse cytology, 5,726 women with a positive HPV test by either of the first-generation HPV DNA assays used in the study (Amplicor HPV test and Linear Array HPG genotyping), and 1,041 women who were HPV negative and who had negative for intraepithelial or malignant (NILM) cervical cytology, showed that the cobas HPV test was significantly more sensitive for detecting CIN 3 or worse than was liquid-based cytology at a threshold of ASCUS or worse (92% vs.
Women ages 21 to 30 will be screened every two years instead of every year, using the slide Pap or liquid-based cytology.
The liquid-based cytology system increases the chances of detecting important abnormalities of the cervix, which if left untreated, may eventually lead to cancer.
The introduction of liquid-based cytology, such as the ThinPrep[R] Pap Test[TM], has had the effect of improving the sensitivity of conventional cytologic screening with the potential for HPV testing of residual cellular material in borderline or difficult cases (5-7).
Liquid-based cytology takes a swab from the cervix using a brush, which is then suspended in a liquid, a more accurate test for picking up cell changes that could develop into cancer.
But the society considered this possibility and recommended the following in its guidelines: "Should the FDA approve HPV DNA testing for this purpose, it would be reasonable to consider that for women aged 30 and over, as an alternative to cervical cytology testing alone, cervical screening may be performed every 3 years using conventional or liquid-based cytology combined with a test for DNA from high-risk HPV types.
75million on switching to liquid-based cytology, which reduces the chance of smear test samples being damaged.
Managing director Terry Hammett will run CellPath's sales team, while Adrian Jackson relinquishes his European export director's role to concentrate on developing sales of the company's AutoCyte PREP liquid-based cytology system in the UK and Republic of Ireland.
Lee said, "Milford Medical Laboratory will perform nested PCR with short target DNA sequencing for HPV genotyping on liquid-based cytology samples referred by S.

Full browser ?