liposome


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liposome

 [lip´o-sōm]
a microscopic spherical particle formed by a lipid bilayer enclosing an aqueous compartment.

lip·o·some

(lip'ō-sōm),
1. A spheric particle of lipid substance suspended in an aqueous medium within a tissue.
2. Any small, roughly spheric artificial vesicle consisting of a lipid bilayer enclosing some of the suspending medium.
[lipo- + G. sōma, body]

liposome

(lĭp′ə-sōm′, lī′pə-)
n.
A microscopic artificial vesicle consisting of an aqueous core enclosed in phospholipid molecules, used to convey vaccines, drugs, or other substances to target tissues.

lip′o·so′mal adj.

liposome

Lipid vesicle Drug delivery A synthetic, uniform bilayer lipid membrane-bound vesicle formed by emulsification of cell membranes in dilute salt solutions, which is used to deliver toxic drugs–eg, amphotericin B, doxorubicin, pentavalent antimony–tagging them with an organ-specific antibody. See Liposome-encapsulated amphotericin B, Stealth liposome.

liposome

an artificially constructed PHOSPHOLIPID VESICLE, which can be used in various biological experiments. Certain drugs may be incorporated into liposomes in order to administer them. In this way the drugs may be protected from degradation and may not exert general toxicity when introduced into the bloodstream.

Liposome

Fat molecule made up of layers of lipids.
Mentioned in: Gene Therapy
References in periodicals archive ?
Indeed, many modifications of the liposome itself can dramatically influence the innate immune response and, thereby, augment or qualitatively modify also the adaptive immune response.
"Our catalogue contains the polycarbonate membranes, common lipids, small-scale extruders as well as proteins in liposomes or micelles." Add Joanna, the chief marketing staff in Creative Biostructure, "Our high quality liposome products are prepared by experienced formulators using the highest quality lipids."
"A novel dexamethasone-loaded liposome alleviates rheumatoid arthritis in rats." International journal of pharmaceutics, 540(1-2): pp.57-64 (2018).
Liposome formulation of purified soybean phosphatidylcholine extract from argomulyo variety soy to replace the toxicity of injectable phosphatidylcholine solution containing sodium deoxycholate.
Liposome Technology: Liposome Preparation and Related Techniques.
The pegylated liposome (Lpeg) was made from DSPC, CHOL, and DSPE-PEG at molar ratios of 5: 4: 0.3 at 76.9 g/L.
(a) Thermal effect induced doxorubicin release from uncoated liposomes and gold liposomes under programed bulk heating from 30 to 50[degrees]C; (b) nanosecond-pulsed laser-triggered doxorubicin release as a function of laser pulse number and influence; 1-100, 1 represents pulse number and 100 represents laser pulse influence (mJ/[cm.sup.2]); (c) kinetics of doxorubicin release upon ns-pulsed laser irradiation (10 pulses, 100 mJ/[cm.sup.2]); (d) gold liposome permeability characterized by carboxyfluorescein (CF) leakage studies (10 pulses, 100 mJ/[cm.sup.2]).
Bhandari, "Liposome: methods of preparation and applications," International Journal of Pharmaceutical Studies and Research, vol.
Brunetto et al., "Liposomal lidocaine gel for topical use at the oral mucosa: Characterization, in vitro assays and in vivo anesthetic efficacy in humans," Journal of Liposome Research, vol.
The liposome sample with thiol-surface modification was radiolabeled with [sup.99m]Tc-tricarbonyl complex [[[sup.99m]Tc[(CO).sub.3][([H.sub.2]O).sub.3]].sup.+] using a commercial kit (Isolink[R], Mallinckrodt Medical B.V.), according to the manufacturer's instructions.
Next, we look for any differences between two different subpopulations of MDSCs, [CD11b.sup.+]Ly6[C.sup.+]Ly6[G.sup.-] and [CD11b.sup.+]Ly6[G.sup.+]Ly6[C.sup.-], and whether those populations could change their recruitment when we injected clodronateloaded liposomes in diabetic animals.