liposomal daunorubicin

liposomal daunorubicin

an aqueous solution of the citrate salt of daunorubicin encapsulated within specifically constructed liposomes that shows enhanced selectivity for solid tumors in situ compared with that of the hydrochloride salt. It is administered intravenously in the treatment of advanced Kaposi's sarcoma associated with acquired immunodeficiency syndrome.
Mentioned in ?
References in periodicals archive ?
61) When treatment is indicated, the use of pegylated liposomal doxorubicin or liposomal daunorubicin is usually recommended as first line treatment.
For initial chemotherapy treatment, it is recommended to use a liposomal anthracycline (either pegylated liposomal doxorubicin or liposomal daunorubicin [evidence level 1b]).
Randomized phase III trial of liposomal daunorubicin versus doxorubicin, bleomycin, and vincristine in AIDS-related Kaposi's sarcoma.
The Phase I study enrolled 18 patients with biopsy-proven AIDS-related KS, 17 of whom had suffered recurrent disease following prior therapy with drugs such as liposomal daunorubicin, paclitaxel and liposomal doxorubicin, and 14 of whom were receiving highly active anti-retroviral therapy.